HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: WSB2 (Q9NYS7)
WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)
Gene: WSB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17079684
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 404
+	Hs
		921886 CUL4A_HUMAN (1-759): 0: 958: 100.00		COPA_HUMAN (32-334): 2.29e-46: 172: 16.57
+	Hs
		1115406 CUL4B_HUMAN (10-759): 0: 922: 82.31		TBL1R_HUMAN (2-228): 7.4e-51: 180: 15.55
+	Hs
		964928 CUL4A_HUMAN (1-759): 0: 958: 100.00		WDR5_HUMAN (281-403): 5.8e-33: 128: 14.06
+	Hs
		261407 CUL4B_HUMAN (10-759): 0: 922: 82.31		TBL1X_HUMAN (182-402): 1.66e-43: 161: 14.48
+	Hs
		1114921 CUL4A_HUMAN (1-759): 0: 958: 100.00		WDR5B_HUMAN (269-403): 6.98e-30: 119: 14.29
+	Hs
		1114950 CUL4A_HUMAN (1-759): 0: 958: 100.00		POC1B_HUMAN (278-401): 7.12e-28: 116: 20.93
+	Hs
		1114994 CUL4A_HUMAN (1-759): 0: 958: 100.00		SNR40_HUMAN (278-402): 7.01e-25: 106: 13.64
+	Hs
		1115179 CUL4A_HUMAN (1-759): 0: 958: 100.00		WSB1_HUMAN (2-181): 3.63e-24: 105: 14.36
+	Hs
		1115343 CUL4B_HUMAN (10-759): 0: 922: 82.31		FBXW7_HUMAN (1-177): 1.54e-35: 140: 12.43
+	Hs
		964929 CUL4B_HUMAN (10-759): 0: 922: 82.31		WDR5_HUMAN (281-403): 5.8e-33: 128: 14.06
+	Hs
		1115283 CUL4B_HUMAN (10-759): 0: 922: 82.31		WDR5B_HUMAN (269-403): 6.98e-30: 119: 14.29
+	Hs
		1115313 CUL4B_HUMAN (10-759): 0: 922: 82.31		POC1B_HUMAN (278-401): 7.12e-28: 116: 20.93
+	Hs
		845297 CUL4A_HUMAN (1-759): 0: 958: 100.00		LIS1_HUMAN (327-404): 5.33e-15: 78.1: 13.25
+	Hs
		1115353 CUL4B_HUMAN (10-759): 0: 922: 82.31		SNR40_HUMAN (278-402): 7.01e-25: 106: 13.64
+	Hs
		845298 CUL4B_HUMAN (10-759): 0: 922: 82.31		LIS1_HUMAN (327-404): 5.33e-15: 78.1: 13.25
+	Hs
		921885 CUL3_HUMAN (32-759): 0: 810: 38.23		COPA_HUMAN (32-334): 2.29e-46: 172: 16.57
+	Hs
		964927 CUL3_HUMAN (32-759): 0: 810: 38.23		WDR5_HUMAN (281-403): 5.8e-33: 128: 14.06
+	At
		1192510 CUL4_ARATH (24-759): 0: 857: 57.40		PRL1_ARATH (31-332): 3.1e-13: 72.8: 22.84
+	Hs
		1113779 CUL3_HUMAN (32-759): 0: 810: 38.23		POC1B_HUMAN (278-401): 7.12e-28: 116: 20.93
+	Hs
		1113186 CUL3_HUMAN (32-759): 0: 810: 38.23		TAF5_HUMAN (29-192): 1.91e-24: 107: 24.41