HitPredict

Interactor 1: USH1G (Q495M9)
pre-mRNA splicing regulator USH1G (Scaffold protein containing ankyrin repeats and SAM domain) (Usher syndrome type-1G protein)
Gene: USH1G

Interactor 2: USH1C (Q9Y6N9)
Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein)
Gene: USH1C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 27173435, 29997244, 28514442, 26264872, 33961781, 20142502, 32814053, 25502805, 31515488
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, molecular sieving, x-ray crystallography, isothermal titration calorimetry, pull down, tandem affinity purification, luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~SAM_1
Common GO terms GO:0001917 - photoreceptor inner segment
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007605 - sensory perception of sound
GO:0030507 - spectrin binding
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024