HitPredict

Interactor 1: FHL3 (Q13643)
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
Gene: FHL3

Interactor 2: KLF12 (Q9Y4X4)
Krueppel-like factor 12 (Transcriptional repressor AP-2rep)
Gene: KLF12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 280 Hs			1 402
+	Hs
		944650 FHL3_HUMAN (1-280): 8.02e-78: 239: 100.00		KLF3_HUMAN (20-402): 1.84e-72: 231: 38.48
+	Hs
		1123183 FHL2_HUMAN (4-156): 7.56e-25: 101: 26.45		KLF12_HUMAN (1-402): 9.36e-118: 350: 100.00
+	Hs
		870167 LIMS1_HUMAN (37-278): 1.09e-45: 158: 23.48		ZN160_HUMAN (52-401): 1.53e-71: 241: 15.22
+	Hs
		1044331 FHL2_HUMAN (4-156): 7.56e-25: 101: 26.45		ZNF85_HUMAN (53-401): 6.04e-87: 277: 14.25
+	Hs
		1036845 FHL2_HUMAN (4-156): 7.56e-25: 101: 26.45		SP4_HUMAN (92-399): 3.97e-67: 228: 29.52
+	Hs
		1123005 FHL2_HUMAN (4-156): 7.56e-25: 101: 26.45		ZN626_HUMAN (141-400): 3.37e-67: 223: 17.41
+	Hs
		892423 PDLI7_HUMAN (3-157): 1.87e-47: 165: 26.45		ZN165_HUMAN (150-401): 1.73e-29: 121: 15.73
+	Hs
		464952 FHL1_HUMAN (66-279): 2.76e-43: 151: 29.17		SP1_HUMAN (308-399): 8.47e-25: 108: 54.35
+	Hs
		1216153 FHL5_HUMAN (4-161): 1.89e-22: 95.7: 27.50		ZN251_HUMAN (43-346): 1.2e-38: 148: 9.23
+	Hs
		599992 FHL1_HUMAN (66-279): 2.76e-43: 151: 29.17		ZNF16_HUMAN (3-165): 5.24e-13: 72.7: 7.98
+	Hs
		167282 FHL5_HUMAN (4-161): 1.89e-22: 95.7: 27.50		KLF11_HUMAN (284-400): 1.25e-30: 124: 56.41
+	Hs
		464956 FHL2_HUMAN (4-156): 7.56e-25: 101: 26.45		SP1_HUMAN (308-399): 8.47e-25: 108: 54.35
+	Hs
		600228 FHL2_HUMAN (4-156): 7.56e-25: 101: 26.45		ZNF23_HUMAN (38-167): 4.38e-12: 69.7: 7.09
+	Hs
		600495 FHL2_HUMAN (4-156): 7.56e-25: 101: 26.45		ZNF3_HUMAN (113-233): 1.69e-11: 67.5: 6.50
+	Hs
		600231 FHL5_HUMAN (4-161): 1.89e-22: 95.7: 27.50		ZNF23_HUMAN (38-167): 4.38e-12: 69.7: 7.09
+	Mm
		266984 FHL2_MOUSE (127-278): 9.29e-25: 101: 26.62		Q199A7_MOUSE (301-371): 1.8e-10: 63.5: 44.16