HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	26186194, 28514442, 33961781, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 262 Hs			1 282
+	Hs
		1040368 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Zm
		9810 B4F8E1_MAIZE (5-181): 1.38e-33: 122: 36.16		A0A1D6EZQ5_MAIZE (6-277): 7.27e-46: 162: 15.07
+	Hs
		266904 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		516744 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		266958 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		1031314 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		516466 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		925150 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		516495 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		516339 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		925003 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Mm
		925159 SRSF3_MOUSE (1-95): 1.17e-25: 100: 35.79		TRA2B_MOUSE (1-279): 2.66e-34: 127: 52.30
+	Hs
		925007 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		516451 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Zm
		30171 A0A1D6M1U3_MAIZE (5-127): 1.28e-19: 88.5: 27.20		A0A1D6K4S7_MAIZE (109-196): 6.8e-27: 110: 35.23
+	Hs
		680437 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		TIA1_HUMAN (114-207): 1.64e-18: 86.4: 21.28
+	Mm
		857332 SRSF2_MOUSE (4-90): 1.89e-24: 99.3: 45.65		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Mm
		665745 PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Hs
		951962 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		CIRBP_HUMAN (121-193): 2.19e-10: 60.1: 58.90
+	Sc
		376562 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		PABP_YEAST (12-109): 4.14e-09: 59: 9.18