Interactor 1: PDCD4 (Q53EL6)
Programmed cell death protein 4 (Neoplastic transformation inhibitor protein) (Nuclear antigen H731-like) (Protein 197/15a)
Gene: PDCD4

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 17053147, 25900982, 26091241, 28514442, 33961781, 22586265, 22669845, 18296647, 23056346
Identification Methods enzymatic study, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 469
Hs

1 605
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024