HitPredict

Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0045296 - cadherin binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 1025
+	Hs
		1124664 SRC8_HUMAN (1-550): 0: 561: 100.00		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		772797 SRC8_HUMAN (1-550): 0: 561: 100.00		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		1124594 SRC8_HUMAN (1-550): 0: 561: 100.00		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96
+	Hs
		1250804 PACN2_HUMAN (176-550): 1.85e-40: 154: 15.37		MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00
+	Hs
		1250770 PACN1_HUMAN (241-549): 2.38e-31: 128: 16.86		MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00
+	Hs
		1459685 PACN2_HUMAN (176-550): 1.85e-40: 154: 15.37		SWP70_HUMAN (370-824): 7.3e-58: 212: 19.22
+	Hs
		1235026 PACN2_HUMAN (176-550): 1.85e-40: 154: 15.37		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		1117489 SPTN1_HUMAN (213-549): 8.25e-34: 139: 14.12		PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24
+	Hs
		250297 VINEX_HUMAN (254-546): 4.07e-13: 73.9: 13.51		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		772771 MYO1E_HUMAN (165-549): 9.91e-45: 172: 15.01		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		250270 VINEX_HUMAN (254-546): 4.07e-13: 73.9: 13.51		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		1133104 LASP1_HUMAN (358-547): 4.31e-13: 71.4: 22.93		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		772789 SPTN1_HUMAN (213-549): 8.25e-34: 139: 14.12		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		1431723 PACN2_HUMAN (176-550): 1.85e-40: 154: 15.37		TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98
+	Hs
		556923 SPTN1_HUMAN (213-549): 8.25e-34: 139: 14.12		MYH7_HUMAN (558-1009): 8.37e-12: 72.1: 10.92
+	Hs
		1117369 SPTN1_HUMAN (213-549): 8.25e-34: 139: 14.12		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96
+	Hs
		1417651 PACN1_HUMAN (241-549): 2.38e-31: 128: 16.86		TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98
+	Hs
		320218 SRBS2_HUMAN (447-549): 1.7e-11: 69.2: 21.91		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		1154118 ITSN1_HUMAN (165-548): 6.15e-15: 80.5: 11.99		MYH14_HUMAN (595-972): 3.71e-09: 63.1: 14.89