HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.532

Property	Details
Experiments	16189514
Identification Methods	two hybrid, affinity chromatography technology, pull down, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2229 Hs			1 1210
+	Hs
		1296398 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		862053 PRC2B_HUMAN (1-2229): 0: 619: 100.00		DAPK1_HUMAN (672-1049): 2.27e-52: 203: 17.06
+	Hs
		1127642 PRC2B_HUMAN (1-2229): 0: 619: 100.00		ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09
+	Hs
		1300945 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		257620 PRC2B_HUMAN (1-2229): 0: 619: 100.00		ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86
+	Mm
		103608 ANK2_MOUSE (294-2229): 1.18e-56: 221: 9.75		ANK3_MOUSE (624-1084): 1.18e-67: 253: 18.00
+	Dm
		65570 FUTSC_DROME (353-2229): 1.74e-50: 201: 9.19		A8JNM5_DROME (552-1104): 5.53e-70: 261: 15.63
+	Hs
		862028 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		DAPK1_HUMAN (672-1049): 2.27e-52: 203: 17.06
+	Hs
		310053 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		TNKS1_HUMAN (490-1119): 3.09e-77: 281: 14.93
+	Hs
		1056981 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		TNKS2_HUMAN (621-1079): 6.56e-72: 264: 19.54
+	Hs
		166913 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		ANR28_HUMAN (263-705): 1.03e-30: 133: 9.87
+	Hs
		556716 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		ANK1_HUMAN (377-765): 2e-59: 227: 14.76
+	Hs
		883487 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		RIPK4_HUMAN (765-1007): 4.14e-26: 118: 16.05
+	Hs
		1021422 MICA3_HUMAN (780-1521): 5.12e-11: 70.6: 11.89		ANK3_HUMAN (624-1084): 7.02e-66: 248: 17.79
+	Hs
		965154 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		Q9H4D1_HUMAN (544-685): 2.91e-12: 73.3: 14.69
+	Hs
		820969 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09
+	Hs
		257726 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86
+	Hs
		166985 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		ANR28_HUMAN (263-705): 1.03e-30: 133: 9.87
+	Hs
		1115387 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		AKD1A_HUMAN (551-707): 1.77e-19: 95.7: 14.47
+	Hs
		257584 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86