Interactor 1: LRRK2 (Q5S006)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-)
Gene: LRRK2

Interactor 2: DNM1L (Q8K1M6)
Dynamin-1-like protein (EC 3.6.5.5) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1)
Gene: DNM1L

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.643

The method score is based on:

Property Details
Experiments 22639965, 29541021, 24282027
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
and 12 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 2527
Mm

1 736
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024