Interactor 1: LDHA (P00338)
L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59)
Gene: LDHA
Interactor 2: LDHB (P07195)
L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46)
Gene: LDHB
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 21516116, 28514442, 34349018, 35235311, 37071682, 36652389, 21988832, 25910212, 32296183, 33961781, 35271311, 31515488, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, two hybrid bait and prey pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ldh_1_C~Ldh_1_C, Ldh_1_C~Ldh_1_N, Ldh_1_N~Ldh_1_N |
| Common GO terms | GO:0004459 - L-lactate dehydrogenase activity GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0006089 - lactate metabolic process GO:0006090 - pyruvate metabolic process and 3 others more... |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
