HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: LRC47 (Q8N1G4)
Leucine-rich repeat-containing protein 47
Gene: LRRC47

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.80	0.637

Property	Details
Experiments	unassigned1853, 24725412
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	LRR_4~LRR_8, LRR_8~LRR_8
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2527 Hs			1 583
+	Hs
		1130636 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		SYFB_HUMAN (285-575): 1.1e-56: 202: 22.80
+	Hs
		2885 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		A0A0G2JPP5_HUMAN (3-409): 5.94e-53: 197: 21.03
+	Hs
		1130604 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		LRC40_HUMAN (52-259): 5.3e-25: 111: 27.96
+	At
		99021 FLS2_ARATH (804-1465): 3.45e-151: 505: 16.05		RGI4_ARATH (4-542): 4.65e-61: 220: 16.04
+	At
		1114725 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		Q9ZVD4_ARATH (2-537): 3.09e-55: 203: 14.95
+	At
		96785 FLS2_ARATH (804-1465): 3.45e-151: 505: 16.05		F4IVP3_ARATH (2-537): 2.81e-55: 203: 14.95
+	At
		1114702 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		TDR_ARATH (1-385): 5.11e-51: 191: 16.50
+	At
		1114712 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		EMS1_ARATH (1-479): 1.53e-46: 177: 15.54
+	At
		1114682 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		ERECT_ARATH (1-434): 1.14e-45: 175: 18.22
+	At
		84593 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		RGI3_ARATH (2-357): 2.98e-43: 168: 15.75
+	At
		1114705 FLS2_ARATH (804-1465): 3.45e-151: 505: 16.05		ERECT_ARATH (1-434): 1.14e-45: 175: 18.22
+	At
		84466 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		GSO1_ARATH (1-375): 2.21e-39: 156: 17.37
+	At
		221761 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		BAME1_ARATH (75-541): 5.03e-38: 152: 14.37
+	At
		1114706 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		PXL1_ARATH (1-288): 2.64e-37: 150: 19.26
+	At
		221778 FLS2_ARATH (804-1465): 3.45e-151: 505: 16.05		BAME1_ARATH (75-541): 5.03e-38: 152: 14.37
+	At
		1114685 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		ERL2_ARATH (130-548): 4.33e-34: 140: 15.80
+	At
		85352 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		ERL1_ARATH (1-255): 4.96e-27: 118: 21.48
+	At
		85369 FLS2_ARATH (804-1465): 3.45e-151: 505: 16.05		ERL1_ARATH (1-255): 4.96e-27: 118: 21.48
+	At
		1114713 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		BAME2_ARATH (1-167): 5.87e-19: 93.2: 20.96
+	At
		249728 FLS2_ARATH (804-1465): 3.45e-151: 505: 16.05		BAME3_ARATH (224-546): 3.67e-11: 68.2: 10.03