Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2
Interactor 2: RAB1B (Q9H0U4)
Ras-related protein Rab-1B (EC 3.6.5.2)
Gene: RAB1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.68 | 1.00 | 0.827 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31046837, 26824392, unassigned1853 |
| Identification Methods | affinity chromatography technology, protein kinase assay, anti tag coimmunoprecipitation |
| Interaction Type | physical association, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Ras, Ras~Roc |
| Common GO terms | GO:0000139 - Golgi membrane GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus and 3 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | At |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
