HitPredict

Interactor 1: HLX (Q14774)
H2.0-like homeobox protein (Homeobox protein HB24) (Homeobox protein HLX1)
Gene: HLX

Interactor 2: Q5T3G3 (Q5T3G3)
TLE family member 1, transcriptional corepressor
Gene: TLE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 242
+	Hs
		1047817 HLX_HUMAN (1-488): 1.73e-69: 231: 100.00		TLE1_HUMAN (1-242): 2.28e-134: 398: 95.87
+	Hs
		1048157 HLX_HUMAN (1-488): 1.73e-69: 231: 100.00		TLE4_HUMAN (1-242): 7.45e-123: 368: 76.45
+	Hs
		1047973 HLX_HUMAN (1-488): 1.73e-69: 231: 100.00		TLE3_HUMAN (1-242): 7.6e-115: 347: 68.85
+	Hs
		662215 PAX7_HUMAN (259-485): 1.61e-35: 140: 23.08		TLE1_HUMAN (1-242): 2.28e-134: 398: 95.87
+	Hs
		1132176 HLX_HUMAN (1-488): 1.73e-69: 231: 100.00		Q5JSZ1_HUMAN (1-215): 5.64e-101: 294: 79.36
+	Hs
		1040480 HHEX_HUMAN (136-396): 1.68e-32: 126: 30.42		TLE1_HUMAN (1-242): 2.28e-134: 398: 95.87
+	Hs
		1047880 HESX1_HUMAN (157-347): 3.64e-32: 123: 19.90		TLE1_HUMAN (1-242): 2.28e-134: 398: 95.87
+	Hs
		662217 PAX7_HUMAN (259-485): 1.61e-35: 140: 23.08		TLE4_HUMAN (1-242): 7.45e-123: 368: 76.45
+	Hs
		814791 CUX1_HUMAN (55-432): 2.28e-34: 139: 17.22		TLE4_HUMAN (1-242): 7.45e-123: 368: 76.45
+	Mm
		148081 BARX2_MOUSE (168-410): 2.86e-36: 137: 25.68		TLE1_MOUSE (1-242): 2.59e-121: 364: 93.80
+	Mm
		666052 PAX3_MOUSE (251-485): 9.51e-33: 132: 22.22		TLE4_MOUSE (1-242): 3.86e-123: 369: 76.45
+	Hs
		662216 PAX7_HUMAN (259-485): 1.61e-35: 140: 23.08		TLE3_HUMAN (1-242): 7.6e-115: 347: 68.85
+	Hs
		814790 CUX1_HUMAN (55-432): 2.28e-34: 139: 17.22		TLE3_HUMAN (1-242): 7.6e-115: 347: 68.85
+	Hs
		1061697 HLX_HUMAN (1-488): 1.73e-69: 231: 100.00		TLE5_HUMAN (1-210): 2.98e-84: 250: 61.43
+	Hs
		1040481 HHEX_HUMAN (136-396): 1.68e-32: 126: 30.42		TLE3_HUMAN (1-242): 7.6e-115: 347: 68.85
+	Hs
		1047907 HLX_HUMAN (1-488): 1.73e-69: 231: 100.00		TLE2_HUMAN (1-242): 2.65e-74: 241: 58.94
+	Dm
		517330 HMH2_DROME (273-393): 4.39e-35: 137: 54.10		GROU_DROME (1-241): 1.3e-90: 283: 50.62
+	Hs
		662219 PAX7_HUMAN (259-485): 1.61e-35: 140: 23.08		TLE5_HUMAN (1-210): 2.98e-84: 250: 61.43
+	Hs
		1040484 HHEX_HUMAN (136-396): 1.68e-32: 126: 30.42		TLE5_HUMAN (1-210): 2.98e-84: 250: 61.43
+	Ce
		146053 HM24_CAEEL (175-339): 1.8e-33: 130: 29.63		UNC37_CAEEL (18-234): 2.06e-56: 191: 27.85