HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: MYO5B (Q9ULV0)
Unconventional myosin-Vb
Gene: MYO5B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	34349018, 35575683, 38334954
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 1848
+	Hs
		773076 MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62		MYO5B_HUMAN (1-1848): 0: 1259: 100.00
+	Hs
		773100 MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62		MYO5A_HUMAN (1-1848): 0: 1179: 61.80
+	Hs
		773040 MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62		MYO5C_HUMAN (1-1848): 0: 1035: 46.84
+	Hs
		1142013 EEA1_HUMAN (70-766): 2.58e-24: 114: 15.40		MYO15_HUMAN (69-856): 0: 947: 37.22
+	Hs
		1105663 GOGA4_HUMAN (921-2109): 5.83e-32: 139: 9.75		MYO10_HUMAN (5-998): 0: 877: 31.04
+	Hs
		1141953 EEA1_HUMAN (70-766): 2.58e-24: 114: 15.40		MYO10_HUMAN (5-998): 0: 877: 31.04
+	Dd
		476420 MYS2_DICDI (591-1663): 8.85e-11: 69.7: 20.16		MYS2_DICDI (63-1442): 9.44e-157: 533: 30.97
+	Hs
		556892 MYH7_HUMAN (1184-2115): 2.78e-36: 153: 10.65		MYH7_HUMAN (713-1715): 6.69e-46: 184: 9.31
+	Hs
		556902 MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62		MYH7_HUMAN (713-1715): 6.69e-46: 184: 9.31
+	Mm
		563088 MYH6_MOUSE (1184-2115): 3.71e-35: 150: 10.76		MYH8_MOUSE (759-1531): 2.41e-35: 150: 11.57
+	Hs
		562992 MYH6_HUMAN (1184-2115): 1.34e-34: 148: 10.30		MYH6_HUMAN (758-1597): 8.73e-33: 142: 11.85
+	Rn
		386940 MYH6_RAT (1184-2115): 3.93e-34: 146: 10.51		MYH6_RAT (742-1506): 3.76e-31: 136: 11.10
+	Mm
		1037835 MYH6_MOUSE (1184-2115): 3.71e-35: 150: 10.76		MYH1_MOUSE (833-1487): 7.31e-26: 119: 13.75
+	Hs
		563081 MYH8_HUMAN (1083-2115): 4.32e-37: 156: 10.06		MYH4_HUMAN (827-1399): 1.48e-23: 111: 13.35
+	Hs
		556973 MYH7_HUMAN (1184-2115): 2.78e-36: 153: 10.65		MYH4_HUMAN (827-1399): 1.48e-23: 111: 13.35
+	Hs
		535921 MYH3_HUMAN (930-1731): 1.32e-24: 115: 12.39		MYH6_HUMAN (758-1597): 8.73e-33: 142: 11.85
+	Hs
		563056 EEA1_HUMAN (70-766): 2.58e-24: 114: 15.40		MYH8_HUMAN (806-1396): 4.98e-24: 113: 13.93
+	Hs
		535958 MYH3_HUMAN (930-1731): 1.32e-24: 115: 12.39		MYH4_HUMAN (827-1399): 1.48e-23: 111: 13.35