Interactor 1: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC
Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.68 | 1.00 | 0.827 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CH~CH, CH~EF-hand_7, CH~Spectrin, Plectin~Plectin, SH3_10~Spectrin, SH3_10~Spectrin_3, Spectrin_2~Spectrin_2, Spectrin_2~Spectrin_3, Spectrin~Spectrin_3, Spectrin_3~Spectrin_3 |
| Common GO terms | GO:0003723 - RNA binding GO:0005886 - plasma membrane GO:0042060 - wound healing GO:0045104 - intermediate filament cytoskeleton organization GO:0045296 - cadherin binding and 1 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
