HitPredict

Interactor 1: EGFLA (Q63HQ2)
Pikachurin (Agrin-like protein) (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)
Gene: EGFLAM

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	25900982, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~fn3
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1017 Hs			1 605
+	Hs
		1144538 EGFLA_HUMAN (20-1017): 0: 661: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		804311 NOTC1_HUMAN (253-786): 4.36e-24: 112: 10.96		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		957555 PGBM_HUMAN (718-877): 4.56e-10: 66.3: 12.12		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Dm
		1375914 X2JE09_DROME (589-779): 3.52e-10: 66.7: 15.03		FBXW7_DROME (414-604): 1.53e-53: 199: 30.73
+	Hs
		804333 NOTC1_HUMAN (253-786): 4.36e-24: 112: 10.96		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67