Protein: SKAP1
Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55)

Gene: SKAP1
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q86WV1

Gene Ontology (top 5):
GO:0001772 - immunological synapse
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0002250 - adaptive immune response
GO:0002821 - positive regulation of adaptive immune response
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

178091

FYB1
FYN-binding protein 1

5

14

Small-scale

0.941

High

440618

FYN
Tyrosine-protein kinase Fyn

4

20

Small-scale

0.890

High

74041

MYO9A
Unconventional myosin-IXa

3

12

High-throughput

0.861

High

286777

SKAP2
Src kinase-associated phosphoprotein 2

3

19

High-throughput

0.861

High

331773

MTMR5
Myotubularin-related protein 5

3

8

High-throughput

0.861

High

909073

NEK4
Serine/threonine-protein kinase Nek4

3

20

High-throughput

0.861

High

1243013

PKN3
Serine/threonine-protein kinase N3

3

20

High-throughput

0.861

High

1292800

NEK1
Serine/threonine-protein kinase Nek1

3

20

High-throughput

0.861

High

1292781

KSR1
Kinase suppressor of Ras 1

2

20

High-throughput

0.789

High

1280654

PKHH3
Pleckstrin homology domain-containing family H member 3

3

9

High-throughput

0.770

High

440135

LCK
Tyrosine-protein kinase Lck

2

20

Small-scale

0.768

High

1237901

PHLB3
Pleckstrin homology-like domain family B member 3

2

18

High-throughput

0.705

High

1292801

PRAM
PML-RARA-regulated adapter molecule 1

4

9

High-throughput

0.698

High

987747

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.691

High

316409

RMP
Unconventional prefoldin RPB5 interactor 1

4

1

High-throughput

0.691

High

136409

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

3

20

High-throughput

0.667

High

165056

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

5

High-throughput

0.667

High

213188

CP110
Centriolar coiled-coil protein of 110 kDa

3

1

High-throughput

0.667

High

228914

CF410
Cilia- and flagella-associated protein 410

3

13

High-throughput

0.667

High

287961

MYCB2
E3 ubiquitin-protein ligase MYCBP2

3

6

High-throughput

0.667

High

315747

RECQ4
ATP-dependent DNA helicase Q4

3

18

High-throughput

0.667

High

340001

RPA1
DNA-directed RNA polymerase I subunit RPA1

3

5

High-throughput

0.667

High

662320

PAX3
Paired box protein Pax-3

3

4

High-throughput

0.667

High

1112372

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

3

3

High-throughput

0.667

High

1122935

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

3

17

High-throughput

0.667

High

1292783

ASPM
Abnormal spindle-like microcephaly-associated protein

3

20

High-throughput

0.667

High

1292785

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

3

12

High-throughput

0.667

High

1292787

PPHLN
Periphilin-1

3

1

High-throughput

0.667

High

1292792

APBP2
Amyloid protein-binding protein 2

3

11

High-throughput

0.667

High

1292804

KLDC3
Kelch domain-containing protein 3

3

6

High-throughput

0.667

High

1292805

SETD5
Histone-lysine N-methyltransferase SETD5

3

1

High-throughput

0.667

High

1292810

RPA2
DNA-directed RNA polymerase I subunit RPA2

3

3

High-throughput

0.667

High

1292825

TASOR
Protein TASOR

3

1

High-throughput

0.667

High

1292826

TTF2
Transcription termination factor 2

3

12

High-throughput

0.667

High

463624

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.647

High

557366

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.647

High

273353

NPHP4
Nephrocystin-4

3

0

High-throughput

0.638

High

1292806

RPA49
DNA-directed RNA polymerase I subunit RPA49

3

0

High-throughput

0.638

High

1214843

EEIG1
Early estrogen-induced gene 1 protein

2

1

High-throughput

0.628

High

168866

PLD2
Phospholipase D2

1

1

High-throughput

0.618

High

1157536

PKN2
Serine/threonine-protein kinase N2

1

20

High-throughput

0.618

High

1292780

SKAP1
Src kinase-associated phosphoprotein 1

1

19

Small-scale

0.618

High

1292789

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

1

15

High-throughput

0.618

High

1292828

TBL2
Transducin beta-like protein 2

1

20

High-throughput

0.618

High

190981

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

6

High-throughput

0.611

High

1106209

MYO9B
Unconventional myosin-IXb

2

12

High-throughput

0.611

High

1181480

EMAL3
Echinoderm microtubule-associated protein-like 3

2

14

High-throughput

0.611

High

1270296

SPT6H
Transcription elongation factor SPT6

2

5

High-throughput

0.611

High

1292782

TRM44
Probable tRNA

2

1

High-throughput

0.611

High

1292788

ALMS1
Centrosome-associated protein ALMS1

2

5

High-throughput

0.611

High

1292812

JPH1
Junctophilin-1

2

4

High-throughput

0.611

High

1292816

UCKL1
Uridine-cytidine kinase-like 1

2

3

High-throughput

0.611

High

1292818

RTEL1
Regulator of telomere elongation helicase 1

2

3

High-throughput

0.611

High

1198305

TIGD5
Tigger transposable element-derived protein 5

3

2

High-throughput

0.609

High

1258125

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

3

1

High-throughput

0.609

High

1292797

REXO5
RNA exonuclease 5

3

9

High-throughput

0.609

High

1292807

ZN644
Zinc finger protein 644

3

2

High-throughput

0.609

High

1292823

ZNHI2
Zinc finger HIT domain-containing protein 2

3

1

High-throughput

0.609

High

983673

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

0

High-throughput

0.585

High

1292813

PDRG1
p53 and DNA damage-regulated protein 1

2

0

High-throughput

0.585

High

1292821

UXT
Protein UXT

2

0

High-throughput

0.585

High

463146

YES
Tyrosine-protein kinase Yes

1

20

High-throughput

0.575

High

1292808

SH24A
SH2 domain-containing protein 4A

1

20

High-throughput

0.573

High

282895

Z324A
Zinc finger protein 324A

2

1

High-throughput

0.558

High

1292815

BCD1
Box C/D snoRNA protein 1

2

1

High-throughput

0.558

High

471748

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

15

Small-scale

0.552

High

986900

BLCAP
Apoptosis inducing factor BLCAP

1

0

High-throughput

0.549

High

1186275

MA7D1
MAP7 domain-containing protein 1

1

14

High-throughput

0.536

High

1211578

C2D1B
Coiled-coil and C2 domain-containing protein 1B

1

6

High-throughput

0.536

High

1214721

ATD3B
ATPase family AAA domain-containing protein 3B

1

16

High-throughput

0.536

High

1291540

HOOK3
Protein Hook homolog 3

1

20

High-throughput

0.536

High

1292819

SENP1
Sentrin-specific protease 1

1

2

High-throughput

0.536

High

1135219

Q149M6
Exophilin 5

2

1

High-throughput

0.533

High

452315

PDIA1
Protein disulfide-isomerase

1

7

High-throughput

0.515

High

936920

CASP7
Caspase-7

1

2

High-throughput

0.515

High

422484

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

949260

MYPR
Myelin proteolipid protein

1

0

High-throughput

0.493

High

1292798

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.481

High

1292794

DYL2
Dynein light chain 2, cytoplasmic

1

2

High-throughput

0.481

High

193791

PER1
Period circadian protein homolog 1

1

1

High-throughput

0.479

High

229147

GTPB6
Putative GTP-binding protein 6

1

5

High-throughput

0.479

High

451200

NFL
Neurofilament light polypeptide

1

18

High-throughput

0.479

High

488017

DPOLA
DNA polymerase alpha catalytic subunit

1

3

High-throughput

0.479

High

841208

CNDD3
Condensin-2 complex subunit D3

1

2

High-throughput

0.479

High

1085773

TF3C1
General transcription factor 3C polypeptide 1

1

1

High-throughput

0.479

High

1094307

LCP2
Lymphocyte cytosolic protein 2

1

13

Small-scale

0.479

High

1112903

CUL2
Cullin-2

1

10

High-throughput

0.479

High

1233753

CNDH2
Condensin-2 complex subunit H2

1

1

High-throughput

0.479

High

1275933

SETX
Probable helicase senataxin

1

8

High-throughput

0.479

High

1292791

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

20

High-throughput

0.479

High

1292796

SENP5
Sentrin-specific protease 5

1

2

High-throughput

0.479

High

1292802

ATX2
Ataxin-2

1

10

High-throughput

0.479

High

1292803

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

5

High-throughput

0.479

High

1292809

ELP3
Elongator complex protein 3

1

1

High-throughput

0.479

High

1292814

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.479

High

1292817

TRM1
tRNA

1

2

High-throughput

0.479

High

1292824

MCM8
DNA helicase MCM8

1

11

High-throughput

0.479

High

1292793

HPS3
BLOC-2 complex member HPS3

1

0

High-throughput

0.458

High

1243819

CTR9
RNA polymerase-associated protein CTR9 homolog

1

16

High-throughput

0.445

High

1292790

LEO1
RNA polymerase-associated protein LEO1

1

1

High-throughput

0.445

High

1292795

THOC1
THO complex subunit 1

1

1

High-throughput

0.445

High

134331

RPOM
DNA-directed RNA polymerase, mitochondrial

1

1

High-throughput

0.437

High

1292784

PUSL1
tRNA pseudouridine synthase-like 1

1

1

High-throughput

0.437

High

1292799

DOCK7
Dedicator of cytokinesis protein 7

1

11

High-throughput

0.437

High

1292822

SEC63
Translocation protein SEC63 homolog

1

9

High-throughput

0.437

High

1292827

AP3M1
AP-3 complex subunit mu-1

1

8

High-throughput

0.437

High

911845

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.426

High

361705

F13A
Coagulation factor XIII A chain

1

1

High-throughput

0.407

High

1292786

EXPH5
Exophilin-5

1

1

High-throughput

0.407

High

1216573

PR14L
Protein PRR14L

3

0

High-throughput

0.347

High

1292811

SUCHY
Succinyl-CoA:glutarate CoA-transferase

3

0

High-throughput

0.347

High

1292820

Q9P1I4
PRO0786

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025