Protein: CNKR1
Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR 1) (CNK homolog protein 1) (CNK1) (hCNK1) (Connector enhancer of KSR-like)

Gene: CNKR1, CNKSR1
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q969H4

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005938 - cell cortex
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0030674 - protein-macromolecule adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225488

CYH3
Cytohesin-3

6

18

High-throughput

0.957

High

1149057

CYH1
Cytohesin-1

4

18

High-throughput

0.902

High

1380307

CYH2
Cytohesin-2

4

18

High-throughput

0.902

High

1380312

CYH4
Cytohesin-4

4

18

High-throughput

0.882

High

962352

RHOA
Transforming protein RhoA

2

20

Small-scale

0.815

High

1237910

PHLB3
Pleckstrin homology-like domain family B member 3

2

19

High-throughput

0.726

High

1350256

RHPN1
Rhophilin-1

1

16

Small-scale

0.648

High

401255

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

Small-scale

0.647

High

1095574

LIPA1
Liprin-alpha-1

1

17

Small-scale

0.647

High

1380311

RASF1
Ras association domain-containing protein 1

1

14

Small-scale

0.637

High

578530

BRAF
Serine/threonine-protein kinase B-raf

1

18

High-throughput

0.618

High

1327434

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

1

High-throughput

0.606

High

1380314

TCAF1
TRPM8 channel-associated factor 1

2

1

High-throughput

0.606

High

1359210

Q8WWE8
CYTH4 protein

1

18

High-throughput

0.594

High

271633

LIPA3
Liprin-alpha-3

1

13

Small-scale

0.579

High

1091787

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

1

Small-scale

0.579

High

180890

TIF1A
Transcription intermediary factor 1-alpha

2

20

High-throughput

0.574

High

322437

HAUS5
HAUS augmin-like complex subunit 5

2

1

High-throughput

0.574

High

1316846

ASPM
Abnormal spindle-like microcephaly-associated protein

2

20

High-throughput

0.574

High

320406

SASH1
SAM and SH3 domain-containing protein 1

1

1

Small-scale

0.555

High

1093155

STK4
Serine/threonine-protein kinase 4

1

20

Small-scale

0.553

High

1097719

STK3
Serine/threonine-protein kinase 3

1

20

Small-scale

0.553

High

159109

ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

1

2

Small-scale

0.501

High

705720

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

5

Small-scale

0.501

High

711171

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

10

Small-scale

0.501

High

1090071

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

9

Small-scale

0.501

High

1144539

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

8

Small-scale

0.501

High

1307593

ZDH17
Palmitoyltransferase ZDHHC17

1

20

High-throughput

0.494

High

932411

GALC
Galactocerebrosidase

1

1

High-throughput

0.489

High

1380313

TRI33
E3 ubiquitin-protein ligase TRIM33

1

13

High-throughput

0.489

High

1091740

GNDS
Ral guanine nucleotide dissociation stimulator

1

2

Small-scale

0.479

High

1106646

SMAD4
Mothers against decapentaplegic homolog 4

1

8

High-throughput

0.464

High

1163894

DUS7
Dual specificity protein phosphatase 7

1

4

Small-scale

0.457

High

1380308

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

13

Small-scale

0.457

High

1380310

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

2

Small-scale

0.457

High

1380315

DUS10
Dual specificity protein phosphatase 10

1

4

Small-scale

0.457

High

404298

GCR
Glucocorticoid receptor

1

17

High-throughput

0.437

High

947031

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

1109347

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

3

0

High-throughput

0.352

High

904353

BRCA2
Breast cancer type 2 susceptibility protein

2

0

High-throughput

0.328

High

1347015

PP14C
Protein phosphatase 1 regulatory subunit 14C

1

0

Small-scale

0.261

Low

1380309

G6PC3
Glucose-6-phosphatase 3

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025