HitPredict

Interactor 1: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: CYLD (Q80TQ2)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	18382763, 18174161, 21878516, 19201866
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 442 Mm			1 952
+	Hs
		1036924 SQSTM_HUMAN (1-442): 0: 715: 89.82		CYLD_HUMAN (1-952): 0: 1794: 94.46
+	Hs
		1206067 MIB1_HUMAN (105-228): 1.65e-27: 117: 27.69		CYLD_HUMAN (1-952): 0: 1794: 94.46
+	Hs
		1284695 MIB2_HUMAN (106-219): 7.47e-14: 75.9: 27.59		CYLD_HUMAN (1-952): 0: 1794: 94.46
+	Hs
		320023 HERC2_HUMAN (120-197): 1.35e-11: 69: 32.50		CYLD_HUMAN (1-952): 0: 1794: 94.46