HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3) (Proteasome subunit alpha-2) (alpha-2)
Gene: PSMA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 234
+	Hs
		681100 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA2_HUMAN (1-234): 1e-97: 286: 100.00
+	Hs
		681107 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA5_HUMAN (1-233): 9.54e-98: 286: 30.96
+	Hs
		680778 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSA5_HUMAN (1-233): 9.54e-98: 286: 30.96
+	Dm
		821867 PSA2_DROME (1-178): 4.05e-76: 229: 37.08		PSA5_DROME (1-234): 9.16e-98: 286: 33.88
+	Hs
		681139 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA6_HUMAN (2-234): 8.26e-91: 269: 34.73
+	Hs
		680769 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA1_HUMAN (1-233): 5.15e-90: 267: 30.67
+	Hs
		165261 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA7_HUMAN (6-231): 5.97e-90: 266: 36.52
+	Hs
		680830 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSA6_HUMAN (2-234): 8.26e-91: 269: 34.73
+	Hs
		680768 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSA1_HUMAN (1-233): 5.15e-90: 267: 30.67
+	Hs
		165260 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSA7_HUMAN (6-231): 5.97e-90: 266: 36.52
+	Ce
		1376826 PSA4_CAEEL (1-178): 1.19e-70: 215: 64.61		PSA7_CAEEL (4-233): 9.5e-94: 276: 33.33
+	Hs
		165263 PSA4_HUMAN (1-181): 1.86e-69: 213: 100.00		PSA7_HUMAN (6-231): 5.97e-90: 266: 36.52
+	Hs
		681201 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSMA8_HUMAN (1-212): 3.68e-46: 155: 41.63
+	Hs
		680962 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSMA8_HUMAN (1-212): 3.68e-46: 155: 41.63
+	Hs
		681102 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA4_HUMAN (4-211): 1.25e-42: 146: 38.68
+	Hs
		680771 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSA4_HUMAN (4-211): 1.25e-42: 146: 38.68
+	Hs
		681570 PSA4_HUMAN (1-181): 1.86e-69: 213: 100.00		PSA4_HUMAN (4-211): 1.25e-42: 146: 38.68