HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 998 Hs			1 1121
+	Hs
		932139 EPHA4_HUMAN (4-998): 0: 1233: 62.29		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		931903 EPHA5_HUMAN (6-988): 0: 1209: 62.74		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		710666 EPHA3_HUMAN (25-990): 0: 1206: 62.01		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		710764 EPHA8_HUMAN (32-993): 0: 1120: 57.87		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		710510 EPHA2_HUMAN (29-998): 0: 1085: 50.36		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		181829 EPHB6_HUMAN (32-996): 0: 937: 40.44		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		439855 INSR_HUMAN (284-953): 3.53e-145: 469: 24.57		WDR6_HUMAN (1-1121): 0: 749: 100.00
+	Hs
		439699 INSR_HUMAN (284-953): 3.53e-145: 469: 24.57		RACK1_HUMAN (196-523): 2.93e-47: 173: 17.21
+	Hs
		1088235 MERTK_HUMAN (272-997): 6.41e-151: 475: 21.58		FBW1A_HUMAN (30-284): 7.74e-34: 140: 13.41
+	Hs
		1088230 MERTK_HUMAN (272-997): 6.41e-151: 475: 21.58		FBW1B_HUMAN (258-535): 1.93e-29: 126: 13.88
+	Hs
		1038487 TIE2_HUMAN (331-896): 5.6e-144: 460: 28.60		WDR3_HUMAN (503-1096): 9.65e-22: 104: 10.45
+	Hs
		440482 FYN_HUMAN (627-891): 1.3e-62: 224: 43.45		RACK1_HUMAN (196-523): 2.93e-47: 173: 17.21
+	Hs
		440671 FYN_HUMAN (627-891): 1.3e-62: 224: 43.45		SNR40_HUMAN (200-348): 7.68e-10: 64: 26.58