HitPredict

Interactor 1: SF3B3 (Q15393)
Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)
Gene: SF3B3

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MMS1_N~WD40, CPSF_A~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1217 Hs			1 626
+	Hs
		1148066 SF3B3_HUMAN (1-1217): 0: 1474: 100.00		NLE1_HUMAN (181-575): 2.23e-63: 218: 12.47
+	Hs
		1147988 SF3B3_HUMAN (1-1217): 0: 1474: 100.00		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Hs
		1098349 SF3B3_HUMAN (1-1217): 0: 1474: 100.00		ERCC8_HUMAN (305-532): 1.36e-57: 200: 19.92
+	Hs
		1157935 DDB1_HUMAN (2-1211): 0: 1062: 21.10		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Ce
		233653 O44985_CAEEL (1-1217): 0: 1304: 60.02		LIN53_CAEEL (251-477): 2.76e-20: 95.7: 15.73
+	Mm
		1189832 DDB1_MOUSE (2-1211): 0: 1062: 21.02		DDB2_MOUSE (201-610): 1.92e-92: 293: 20.46
+	At
		1237278 DDB1A_ARATH (2-1211): 0: 1039: 20.03		DDB2_ARATH (244-613): 4.91e-94: 302: 24.31
+	Hs
		1157825 DDB1_HUMAN (2-1211): 0: 1062: 21.10		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Hs
		1157835 DDB1_HUMAN (2-1211): 0: 1062: 21.10		DDB2_HUMAN (201-625): 2.11e-70: 235: 21.51
+	Hs
		1098350 DDB1_HUMAN (2-1211): 0: 1062: 21.10		ERCC8_HUMAN (305-532): 1.36e-57: 200: 19.92
+	Hs
		1157795 DDB1_HUMAN (2-1211): 0: 1062: 21.10		WDR5B_HUMAN (395-624): 5.48e-51: 181: 11.74
+	Hs
		964975 DDB1_HUMAN (2-1211): 0: 1062: 21.10		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		261411 DDB1_HUMAN (2-1211): 0: 1062: 21.10		TBL1X_HUMAN (248-479): 5.35e-39: 153: 13.67
+	Hs
		1157860 DDB1_HUMAN (2-1211): 0: 1062: 21.10		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		1066320 DDB1_HUMAN (2-1211): 0: 1062: 21.10		RBBP4_HUMAN (233-477): 2.85e-19: 92.6: 14.55
+	Hs
		845309 DDB1_HUMAN (2-1211): 0: 1062: 21.10		LIS1_HUMAN (524-623): 3.63e-12: 70.5: 11.00
+	At
		1444135 DDB1A_ARATH (2-1211): 0: 1039: 20.03		SPA2_ARATH (452-626): 1.23e-09: 63.6: 11.24
+	At
		235880 DDB1B_ARATH (1-1211): 0: 1032: 20.10		SPA2_ARATH (452-626): 1.23e-09: 63.6: 11.24
+	Hs
		1083446 CPSF1_HUMAN (701-1216): 4.43e-121: 410: 15.99		NLE1_HUMAN (181-575): 2.23e-63: 218: 12.47
+	Hs
		209255 CPSF1_HUMAN (701-1216): 4.43e-121: 410: 15.99		PRP4_HUMAN (401-624): 8.47e-40: 154: 15.09