HitPredict

Interactor 1: DIXC1 (Q155Q3)
Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)
Gene: DIXDC1

Interactor 2: ULK2 (Q8IYT8)
Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)
Gene: ULK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 683 Hs			1 1036
+	Hs
		637623 FLNA_HUMAN (12-167): 1.04e-45: 178: 24.71		ULK2_HUMAN (1-1036): 0: 900: 100.00
+	Hs
		555754 ACTN1_HUMAN (13-574): 2.88e-138: 428: 16.17		SIK2_HUMAN (9-833): 2.73e-128: 414: 20.39
+	Hs
		224794 ACTN4_HUMAN (16-599): 7.22e-127: 399: 14.63		SIK2_HUMAN (9-833): 2.73e-128: 414: 20.39
+	Hs
		224704 ACTN4_HUMAN (16-599): 7.22e-127: 399: 14.63		KCC2B_HUMAN (8-515): 3.31e-124: 395: 24.09
+	Hs
		862669 UTRN_HUMAN (7-450): 1.08e-93: 320: 19.88		MARK2_HUMAN (2-746): 4.88e-134: 425: 20.19
+	Hs
		692010 UTRN_HUMAN (7-450): 1.08e-93: 320: 19.88		MARK3_HUMAN (2-696): 8.23e-133: 421: 21.25
+	Hs
		862723 UTRN_HUMAN (7-450): 1.08e-93: 320: 19.88		MARK1_HUMAN (2-696): 5.76e-129: 412: 21.60
+	Rn
		1224589 SPTN2_RAT (9-577): 1.45e-99: 337: 18.40		AKT3_RAT (2-342): 1.74e-124: 389: 24.29
+	Ce
		1171146 Q23158_CAEEL (13-576): 9.51e-114: 365: 14.24		UNC51_CAEEL (450-1029): 1.25e-80: 283: 20.75
+	Dm
		1269084 FLNA_DROME (12-167): 4.4e-46: 179: 23.73		Q7KSS0_DROME (7-893): 1.83e-130: 426: 17.71
+	Hs
		637724 FLNA_HUMAN (12-167): 1.04e-45: 178: 24.71		SIK2_HUMAN (9-833): 2.73e-128: 414: 20.39
+	Ce
		116212 H2L2C8_CAEEL (57-576): 1.06e-92: 307: 12.23		UNC51_CAEEL (450-1029): 1.25e-80: 283: 20.75
+	Mm
		1229966 FLNA_MOUSE (12-167): 1.04e-45: 178: 24.71		BRSK2_MOUSE (9-737): 5.59e-125: 400: 21.61
+	Hs
		159719 DVL2_HUMAN (601-680): 8.12e-38: 152: 41.25		MARK2_HUMAN (2-746): 4.88e-134: 425: 20.19
+	Hs
		637795 FLNA_HUMAN (12-167): 1.04e-45: 178: 24.71		AKT3_HUMAN (2-342): 2.01e-127: 397: 24.57
+	Hs
		159516 DVL2_HUMAN (601-680): 8.12e-38: 152: 41.25		MARK3_HUMAN (2-696): 8.23e-133: 421: 21.25
+	Hs
		159891 DVL2_HUMAN (601-680): 8.12e-38: 152: 41.25		MARK1_HUMAN (2-696): 5.76e-129: 412: 21.60
+	Hs
		637690 FLNA_HUMAN (12-167): 1.04e-45: 178: 24.71		KCC1G_HUMAN (9-403): 1.24e-112: 358: 27.25
+	Hs
		1028797 SPTB2_HUMAN (9-577): 5.16e-97: 330: 17.21		ULK3_HUMAN (15-279): 5.94e-53: 194: 39.71