HitPredict

Interactor 1: Q6GQ04 (Q6GQ04)
Cell division cycle protein 27 homolog
Gene: MGC80529

Interactor 2: Q6NU36 (Q6NU36)
Anaphase-promoting complex subunit 4 (Cyclosome subunit 4)
Gene: anapc4.L

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16364912, 20951947
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 833 Xl			1 789
+	Hs
		672919 CDC27_HUMAN (1-833): 0: 553: 89.33		APC4_HUMAN (2-780): 0: 1163: 72.19
+	Hs
		1356134 APC7_HUMAN (309-822): 2.98e-65: 230: 15.92		APC4_HUMAN (2-780): 0: 1163: 72.19
+	Hs
		1135066 Q5T8C6_HUMAN (488-804): 3.05e-57: 205: 19.00		APC4_HUMAN (2-780): 0: 1163: 72.19
+	Hs
		1356111 CDC23_HUMAN (368-800): 1.01e-32: 136: 14.94		APC4_HUMAN (2-780): 0: 1163: 72.19
+	Hs
		1023018 CDC16_HUMAN (371-830): 6.86e-13: 74.2: 10.83		APC4_HUMAN (2-780): 0: 1163: 72.19
+	At
		249656 CD27B_ARATH (574-831): 7.18e-24: 109: 11.28		APC4_ARATH (3-732): 0: 741: 22.95
+	At
		249662 CDC23_ARATH (533-829): 1.67e-18: 91.9: 12.46		APC4_ARATH (3-732): 0: 741: 22.95
+	Sp
		194008 CUT9_SCHPO (481-831): 9.19e-53: 197: 17.39		APC4_SCHPO (23-503): 3.59e-148: 453: 21.56
+	Sp
		194007 APC3_SCHPO (537-826): 4.6e-33: 138: 16.15		APC4_SCHPO (23-503): 3.59e-148: 453: 21.56
+	Sp
		194005 APC8_SCHPO (446-651): 2.53e-12: 72.3: 12.74		APC4_SCHPO (23-503): 3.59e-148: 453: 21.56