HitPredict

Interactor 1: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Interactor 2: ARL8B (Q9NVJ2)
ADP-ribosylation factor-like protein 8B (EC 3.6.5.2) (ADP-ribosylation factor-like protein 10C) (Novel small G protein indispensable for equal chromosome segregation 1)
Gene: ARL8B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0031901 - early endosome membrane GO:0045202 - synapse
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 100 Hs			1 186
+	Hs
		278487 VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00		ARF6_HUMAN (12-183): 8.02e-84: 246: 34.88
+	Hs
		975054 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		ARF6_HUMAN (12-183): 8.02e-84: 246: 34.88
+	Hs
		907997 VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51		ARF6_HUMAN (12-183): 8.02e-84: 246: 34.88
+	Hs
		974971 VAMP2_HUMAN (8-84): 9.13e-23: 86.6: 87.01		ARF6_HUMAN (12-183): 8.02e-84: 246: 34.88
+	Sc
		536076 SEC22_YEAST (1-97): 4.41e-22: 87.3: 18.56		ARF1_YEAST (1-183): 3.2e-83: 245: 32.24
+	Hs
		975212 VAMP8_HUMAN (6-82): 1.06e-22: 85.8: 35.07		ARF6_HUMAN (12-183): 8.02e-84: 246: 34.88
+	Sc
		536088 SNC1_YEAST (6-81): 8.84e-22: 83.9: 32.90		ARF1_YEAST (1-183): 3.2e-83: 245: 32.24
+	Hs
		981286 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		RAB1A_HUMAN (5-185): 5.8e-69: 210: 22.16
+	Hs
		908054 VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51		ARL8B_HUMAN (1-186): 8.25e-70: 211: 100.00
+	Hs
		1154737 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		RAB1B_HUMAN (21-185): 1.23e-67: 206: 23.08
+	Hs
		278486 VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00		RAB2A_HUMAN (21-184): 4.14e-64: 198: 16.67
+	Hs
		956308 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		RAB2A_HUMAN (21-184): 4.14e-64: 198: 16.67
+	Hs
		957934 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		RAB14_HUMAN (21-184): 8.11e-64: 197: 17.86
+	Hs
		907994 VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51		RAB2A_HUMAN (21-184): 4.14e-64: 198: 16.67
+	Hs
		907995 VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51		RAB14_HUMAN (21-184): 8.11e-64: 197: 17.86
+	Hs
		956242 VAMP2_HUMAN (8-84): 9.13e-23: 86.6: 87.01		RAB2A_HUMAN (21-184): 4.14e-64: 198: 16.67
+	Sc
		376268 SEC22_YEAST (1-97): 4.41e-22: 87.3: 18.56		YPT1_YEAST (21-186): 1.8e-63: 196: 21.77