Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2
Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 27705803, 24981860, 33961781, 24457600, 26496610, 27634302, 30779601, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EZH2_WD-Binding~WD40, SET~WD40 |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000781 - chromosome, telomeric region GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 4 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
