Interactor 1: LRC8E (Q6NSJ5)
Volume-regulated anion channel subunit LRRC8E (Leucine-rich repeat-containing protein 8E)
Gene: LRRC8E
Interactor 2: LRC8A (Q8IWT6)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1)
Gene: LRRC8A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24790029 |
| Identification Methods | anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_1~LRR_8, LRR_8~LRR_8, Pannexin_like~Pannexin_like |
| Common GO terms | GO:0005225 - volume-sensitive anion channel activity GO:0005737 - cytoplasm GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0006884 - cell volume homeostasis and 4 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
