HitPredict

Interactor 1: DPYL2 (Q16555)
Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2)
Gene: DPYSL2

Interactor 2: Q8IXW6 (Q8IXW6)
Dihydropyrimidinase-like 3
Gene: DPYSL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Amidohydro_1~Amidohydro_1
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 572 Hs			1 570
+	Hs
		1123248 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL3_HUMAN (1-570): 0: 765: 99.83
+	Hs
		1123192 DPYL1_HUMAN (1-572): 0: 761: 76.22		DPYL3_HUMAN (1-570): 0: 765: 99.83
+	Hs
		1123198 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL1_HUMAN (1-569): 0: 748: 74.43
+	Mm
		1021377 DPYL1_MOUSE (1-572): 0: 752: 76.22		DPYL3_MOUSE (1-570): 0: 764: 98.25
+	Hs
		1158660 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL2_HUMAN (1-569): 0: 742: 76.53
+	Hs
		1123191 DPYL1_HUMAN (1-572): 0: 761: 76.22		DPYL1_HUMAN (1-569): 0: 748: 74.43
+	Mm
		147455 DPYL2_MOUSE (1-572): 0: 768: 98.78		DPYL2_MOUSE (1-569): 0: 740: 77.23
+	Rn
		868848 DPYL2_RAT (1-572): 0: 768: 98.78		DPYL2_RAT (1-569): 0: 740: 77.23
+	Mm
		147494 DPYL2_MOUSE (1-572): 0: 768: 98.78		DPYL1_MOUSE (1-569): 0: 738: 74.43
+	Hs
		155854 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL4_HUMAN (1-570): 0: 730: 70.11
+	Hs
		155850 DPYL1_HUMAN (1-572): 0: 761: 76.22		DPYL4_HUMAN (1-570): 0: 730: 70.11
+	Hs
		1158727 DPYL2_HUMAN (1-572): 0: 769: 100.00		X5DQV1_HUMAN (14-569): 0: 720: 74.19
+	Mm
		1021373 DPYL1_MOUSE (1-572): 0: 752: 76.22		Q3TMU8_MOUSE (1-570): 0: 731: 70.11
+	Hs
		155851 DPYL3_HUMAN (1-571): 0: 744: 76.71		DPYL4_HUMAN (1-570): 0: 730: 70.11
+	Hs
		1120600 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYS_HUMAN (16-522): 0: 649: 58.90
+	Hs
		1158698 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL5_HUMAN (9-565): 0: 649: 50.54
+	Mm
		147582 DPYL2_MOUSE (1-572): 0: 768: 98.78		DPYL5_MOUSE (9-565): 0: 642: 50.36
+	Hs
		1120598 DPYL3_HUMAN (1-571): 0: 744: 76.71		DPYS_HUMAN (16-522): 0: 649: 58.90