HitPredict

Interactor 1: MK06 (Q16659)
Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
Gene: MAPK6

Interactor 2: OSTF1 (Q92882)
Osteoclast-stimulating factor 1
Gene: OSTF1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 721 Hs			1 214
+	Hs
		1091408 MK06_HUMAN (1-721): 0: 640: 100.00		ANK3_HUMAN (8-213): 2.39e-34: 131: 13.98
+	Hs
		1161212 MK06_HUMAN (1-721): 0: 640: 100.00		ANKR2_HUMAN (80-213): 1.17e-31: 119: 23.13
+	Hs
		1161138 MK06_HUMAN (1-721): 0: 640: 100.00		ANKH1_HUMAN (3-128): 7.35e-15: 74.6: 18.90
+	Hs
		703511 MK01_HUMAN (14-354): 1.99e-137: 410: 42.57		DAPK1_HUMAN (3-192): 1.55e-33: 128: 24.08
+	Hs
		668052 CDK2_HUMAN (17-322): 4.44e-134: 399: 31.19		RAI14_HUMAN (3-209): 2.6e-34: 130: 19.23
+	Hs
		691686 MK03_HUMAN (8-360): 1.59e-133: 400: 41.41		DAPK1_HUMAN (3-192): 1.55e-33: 128: 24.08
+	Hs
		177176 MK01_HUMAN (14-354): 1.99e-137: 410: 42.57		ANR28_HUMAN (4-213): 8.05e-20: 88.9: 15.77
+	Mm
		989552 MK01_MOUSE (14-354): 1.32e-137: 410: 42.57		TNKS2_MOUSE (3-213): 1.48e-19: 88.1: 14.74
+	Rn
		989653 MK01_RAT (14-354): 1.32e-137: 410: 42.57		TANC1_RAT (82-195): 1.03e-18: 85.7: 24.14
+	Hs
		703686 MK01_HUMAN (14-354): 1.99e-137: 410: 42.57		BARD1_HUMAN (136-213): 9.57e-17: 80: 20.51
+	Hs
		668005 CDK2_HUMAN (17-322): 4.44e-134: 399: 31.19		BARD1_HUMAN (136-213): 9.57e-17: 80: 20.51
+	Hs
		703703 MK01_HUMAN (14-354): 1.99e-137: 410: 42.57		TNKS2_HUMAN (2-115): 6.32e-09: 57.2: 18.26