HitPredict

Interactor 1: CSKP (Q24210)
Peripheral plasma membrane protein CASK (dCASK) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase) (CAKI) (Camguk)
Gene: CASK

Interactor 2: Q9VBY7 (Q9VBY7)
Protein lin-7 homolog
Gene: veli

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.878

Property	Details
Experiments	15039455, 37061542, 22036573, unassigned2874
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, L27~L27, PDZ~PDZ
Common GO terms	GO:0005911 - cell-cell junction GO:0007269 - neurotransmitter secretion GO:0007298 - border follicle cell migration GO:0008582 - regulation of synaptic assembly at neuromuscular junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 898 Dm			1 195
+	Hs
		168758 CSKP_HUMAN (1-898): 0: 880: 59.11		LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00
+	Mm
		267260 CSKP_MOUSE (1-898): 0: 879: 59.11		LIN7C_MOUSE (1-195): 6.8e-53: 169: 80.00
+	Hs
		168750 CSKP_HUMAN (1-898): 0: 880: 59.11		LIN7B_HUMAN (1-195): 7.6e-52: 167: 77.44
+	Mm
		267259 CSKP_MOUSE (1-898): 0: 879: 59.11		LIN7B_MOUSE (1-195): 5.31e-52: 167: 77.95
+	Hs
		167670 CSKP_HUMAN (1-898): 0: 880: 59.11		LIN7A_HUMAN (6-194): 1.48e-49: 162: 77.78
+	Hs
		168683 CSKP_HUMAN (1-898): 0: 880: 59.11		SNTB2_HUMAN (63-179): 2.85e-31: 120: 35.83
+	Hs
		168687 CSKP_HUMAN (1-898): 0: 880: 59.11		SNTB1_HUMAN (41-179): 3.67e-30: 117: 30.71
+	Hs
		168670 CSKP_HUMAN (1-898): 0: 880: 59.11		DLG4_HUMAN (41-181): 3.38e-26: 106: 26.03
+	Hs
		168680 CSKP_HUMAN (1-898): 0: 880: 59.11		DLG1_HUMAN (60-181): 1.06e-25: 105: 30.71
+	Mm
		267274 CSKP_MOUSE (1-898): 0: 879: 59.11		DLG1_MOUSE (49-181): 8.66e-25: 102: 27.54
+	Rn
		1224257 CSKP_RAT (1-898): 0: 867: 59.55		DLG1_RAT (49-189): 1.36e-24: 102: 26.71
+	Hs
		168730 CSKP_HUMAN (1-898): 0: 880: 59.11		DLG3_HUMAN (82-164): 2.49e-19: 87.1: 36.36
+	Ce
		933112 LIN2_CAEEL (2-898): 0: 762: 44.64		Q9U245_CAEEL (3-195): 1.31e-43: 146: 67.88
+	Hs
		1122734 MPP2_HUMAN (395-898): 1.2e-169: 506: 40.58		LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00
+	Hs
		1122731 MPP2_HUMAN (395-898): 1.2e-169: 506: 40.58		LIN7B_HUMAN (1-195): 7.6e-52: 167: 77.44
+	Hs
		167699 MPP2_HUMAN (395-898): 1.2e-169: 506: 40.58		LIN7A_HUMAN (6-194): 1.48e-49: 162: 77.78
+	Hs
		1437597 PALS2_HUMAN (392-898): 6.11e-163: 488: 39.46		LIN7B_HUMAN (1-195): 7.6e-52: 167: 77.44
+	Hs
		167723 PALS2_HUMAN (392-898): 6.11e-163: 488: 39.46		LIN7A_HUMAN (6-194): 1.48e-49: 162: 77.78
+	Hs
		1091491 MPP2_HUMAN (395-898): 1.2e-169: 506: 40.58		DLG1_HUMAN (60-181): 1.06e-25: 105: 30.71
+	Mm
		1223777 MPP2_MOUSE (392-898): 3.23e-168: 502: 40.54		DLG4_MOUSE (41-181): 2.63e-26: 107: 26.03