HitPredict

Interactor 1: PCGF3 (Q3KNV8)
Polycomb group RING finger protein 3 (RING finger protein 3A)
Gene: PCGF3

Interactor 2: BCOR (Q6W2J9)
BCL-6 corepressor (BCoR)
Gene: BCOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	24981860, 25416956, 27705803, 23523425
Identification Methods	affinity chromatography technology, two hybrid, lambda repressor two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	PUFD~RAWUL
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 242 Hs			1 1755
+	Hs
		765638 BMI1_HUMAN (3-238): 8.59e-60: 193: 33.76		BCOR_HUMAN (1-1755): 0: 2296: 100.00
+	Hs
		766098 PCGF2_HUMAN (3-238): 3.05e-58: 189: 33.76		BCOR_HUMAN (1-1755): 0: 2296: 100.00
+	Hs
		1250649 PCGF1_HUMAN (3-238): 3.33e-45: 153: 39.17		BCOR_HUMAN (1-1755): 0: 2296: 100.00
+	Hs
		1250652 PCGF6_HUMAN (3-235): 5.41e-43: 150: 34.89		BCOR_HUMAN (1-1755): 0: 2296: 100.00
+	Hs
		1250603 PCGF5_HUMAN (4-241): 1.49e-39: 138: 38.06		BCOR_HUMAN (1-1755): 0: 2296: 100.00
+	Hs
		1250642 RING2_HUMAN (2-237): 1e-35: 131: 18.00		BCOR_HUMAN (1-1755): 0: 2296: 100.00
+	Mm
		1298578 RING2_MOUSE (2-237): 7.77e-36: 131: 18.00		BCOR_MOUSE (1-1755): 0: 2253: 88.59
+	Hs
		1185913 PCGF3_HUMAN (1-242): 8.87e-66: 205: 100.00		BCORL_HUMAN (1025-1743): 3.77e-87: 318: 33.88
+	Hs
		765594 BMI1_HUMAN (3-238): 8.59e-60: 193: 33.76		BCORL_HUMAN (1025-1743): 3.77e-87: 318: 33.88
+	Hs
		766096 PCGF2_HUMAN (3-238): 3.05e-58: 189: 33.76		BCORL_HUMAN (1025-1743): 3.77e-87: 318: 33.88
+	Hs
		765897 BMI1_HUMAN (3-238): 8.59e-60: 193: 33.76		EHMT1_HUMAN (808-1668): 2.16e-79: 291: 14.04
+	Hs
		1204633 PCGF1_HUMAN (3-238): 3.33e-45: 153: 39.17		BCORL_HUMAN (1025-1743): 3.77e-87: 318: 33.88
+	Hs
		1204635 PCGF6_HUMAN (3-235): 5.41e-43: 150: 34.89		BCORL_HUMAN (1025-1743): 3.77e-87: 318: 33.88
+	Hs
		1204615 PCGF5_HUMAN (4-241): 1.49e-39: 138: 38.06		BCORL_HUMAN (1025-1743): 3.77e-87: 318: 33.88
+	Hs
		1204631 RING2_HUMAN (2-237): 1e-35: 131: 18.00		BCORL_HUMAN (1025-1743): 3.77e-87: 318: 33.88
+	Mm
		1204125 RING2_MOUSE (2-237): 7.77e-36: 131: 18.00		EHMT1_MOUSE (980-1668): 2.89e-82: 300: 14.17
+	Hs
		765823 BMI1_HUMAN (3-238): 8.59e-60: 193: 33.76		MPP8_HUMAN (1018-1654): 1.99e-63: 236: 16.64
+	Hs
		1396286 RING2_HUMAN (2-237): 1e-35: 131: 18.00		EHMT2_HUMAN (883-1633): 3.43e-79: 289: 13.01
+	Hs
		1091447 RING2_HUMAN (2-237): 1e-35: 131: 18.00		ANK3_HUMAN (1182-1750): 1.25e-73: 276: 12.25
+	Dm
		1305643 Q9VV77_DROME (2-241): 1.13e-49: 163: 54.55		Q8IQT4_DROME (1426-1624): 1.97e-54: 213: 41.87