HitPredict

Interactor 1: GRDN (Q3V6T2)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: CCDC88A

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0042127 - regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1871 Hs			1 1620
+	Hs
		773080 MYH9_HUMAN (1117-1871): 5.15e-30: 132: 9.12		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		773304 MYH10_HUMAN (10-690): 3.42e-24: 113: 12.94		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		1150964 TRIPB_HUMAN (787-1622): 1.83e-18: 95: 10.35		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		711903 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		LTK_HUMAN (606-1458): 2.7e-178: 559: 53.24
+	Hs
		641186 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		FGFR2_HUMAN (952-1433): 1.46e-122: 406: 25.24
+	Hs
		439751 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		650461 DAPLE_HUMAN (3-1838): 2.67e-101: 365: 45.75		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		1159499 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		NTRK2_HUMAN (1093-1375): 7.39e-64: 236: 41.44
+	Hs
		412031 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		541523 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		711898 TRIPB_HUMAN (787-1622): 1.83e-18: 95: 10.35		LTK_HUMAN (606-1458): 2.7e-178: 559: 53.24
+	Hs
		710604 MYH9_HUMAN (1117-1871): 5.15e-30: 132: 9.12		EPHA3_HUMAN (943-1427): 1.05e-119: 403: 25.05
+	Hs
		641181 TRIPB_HUMAN (787-1622): 1.83e-18: 95: 10.35		FGFR2_HUMAN (952-1433): 1.46e-122: 406: 25.24
+	Hs
		650174 TRIPB_HUMAN (787-1622): 1.83e-18: 95: 10.35		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		465525 EEA1_HUMAN (1024-1684): 5.16e-12: 73.4: 9.73		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		411474 MYH9_HUMAN (1117-1871): 5.15e-30: 132: 9.12		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411475 MYH10_HUMAN (10-690): 3.42e-24: 113: 12.94		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		1150908 TRIPB_HUMAN (787-1622): 1.83e-18: 95: 10.35		NTRK2_HUMAN (1093-1375): 7.39e-64: 236: 41.44
+	Hs
		412196 HOOK3_HUMAN (14-554): 1.3e-16: 88.2: 23.48		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		541508 TRIPB_HUMAN (787-1622): 1.83e-18: 95: 10.35		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07