HitPredict

Interactor 1: Q3YMU0 (Q3YMU0)
Protein disulfide-isomerase (EC 5.3.4.1)
Gene: ERp60

Interactor 2: Q9W022 (Q9W022)
GEO01508p1 (RE49388p)
Gene: DmelCG8993

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 489 Dm			1 142
+	Dm
		1191678 Q3YMU0_DROME (1-489): 4.25e-152: 444: 100.00		THIO2_DROME (34-138): 1.25e-35: 120: 31.13
+	Dm
		1191679 Q3YMU0_DROME (1-489): 4.25e-152: 444: 100.00		PDIA6_DROME (9-126): 4.88e-29: 111: 21.01
+	Hs
		717481 PDIA3_HUMAN (2-474): 1.66e-132: 394: 46.42		PDIA6_HUMAN (35-140): 3.11e-33: 122: 24.30
+	Hs
		717371 PDIA3_HUMAN (2-474): 1.66e-132: 394: 46.42		PDIA3_HUMAN (1-137): 4.76e-30: 114: 19.86
+	Hs
		566571 PDIA3_HUMAN (2-474): 1.66e-132: 394: 46.42		PDIA4_HUMAN (35-140): 1.07e-28: 111: 28.44
+	Hs
		452382 PDIA1_HUMAN (15-469): 1.44e-126: 379: 33.05		THIOM_HUMAN (37-139): 4.14e-36: 123: 45.63
+	Hs
		452145 PDIA1_HUMAN (15-469): 1.44e-126: 379: 33.05		PDIA4_HUMAN (35-140): 1.07e-28: 111: 28.44
+	Dm
		929527 PDI_DROME (5-489): 1.94e-114: 348: 32.66		THIO2_DROME (34-138): 1.25e-35: 120: 31.13
+	Dm
		929613 PDI_DROME (5-489): 1.94e-114: 348: 32.66		Q9W022_DROME (1-142): 7.95e-35: 119: 100.00
+	At
		1318507 PDI11_ARATH (3-473): 7.59e-109: 334: 32.44		TRXY2_ARATH (2-142): 2.24e-38: 129: 22.92
+	Dm
		929528 PDI_DROME (5-489): 1.94e-114: 348: 32.66		PDIA6_DROME (9-126): 4.88e-29: 111: 21.01
+	At
		1192558 PDI11_ARATH (3-473): 7.59e-109: 334: 32.44		TRXH3_ARATH (29-130): 7.53e-36: 121: 28.57
+	Ce
		1165053 PDI1_CAEEL (6-487): 2.38e-107: 329: 28.60		PDI2_CAEEL (32-134): 1.04e-11: 62.8: 33.96
+	Hs
		1127909 PDIA5_HUMAN (122-487): 3.77e-36: 142: 14.36		PDIA6_HUMAN (35-140): 3.11e-33: 122: 24.30
+	Hs
		566671 PDIA5_HUMAN (122-487): 3.77e-36: 142: 14.36		PDIA4_HUMAN (35-140): 1.07e-28: 111: 28.44
+	Hs
		566761 TXND5_HUMAN (12-133): 1.16e-30: 125: 33.61		PDIA4_HUMAN (35-140): 1.07e-28: 111: 28.44
+	Mm
		1021743 ERP44_MOUSE (359-488): 2.66e-25: 109: 22.06		THIOM_MOUSE (37-139): 5.09e-36: 123: 46.60
+	Mm
		1362938 ERP44_MOUSE (359-488): 2.66e-25: 109: 22.06		PDIA6_MOUSE (35-132): 1.64e-33: 123: 27.45
+	Mm
		697731 ERP44_MOUSE (359-488): 2.66e-25: 109: 22.06		PDIA3_MOUSE (1-137): 2.66e-29: 112: 18.44
+	Mm
		1362256 ERP44_MOUSE (359-488): 2.66e-25: 109: 22.06		TXND5_MOUSE (14-138): 2.2e-29: 111: 21.71