HitPredict

Interactor 1: USH1G (Q495M9)
pre-mRNA splicing regulator USH1G (Scaffold protein containing ankyrin repeats and SAM domain) (Usher syndrome type-1G protein)
Gene: USH1G

Interactor 2: X5D778 (X5D778)
Ankyrin repeat domain 11 isoform A (Ankyrin repeat domain containing 11)
Gene: ANKRD11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	unassigned1304
Identification Methods	validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ank_2
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 421
+	Hs
		1193175 USH1G_HUMAN (1-461): 1.58e-88: 279: 100.00		ANR11_HUMAN (250-421): 8.52e-56: 201: 100.00
+	Mm
		109271 ANK2_MOUSE (3-460): 8.15e-55: 199: 15.91		ANK3_MOUSE (139-419): 2.68e-53: 193: 16.50
+	Hs
		943916 ANK2_HUMAN (3-410): 7.95e-58: 208: 12.97		RIPK4_HUMAN (70-417): 9.61e-50: 182: 15.27
+	Hs
		943925 ANK3_HUMAN (3-402): 1.92e-57: 207: 12.90		RIPK4_HUMAN (70-417): 9.61e-50: 182: 15.27
+	Hs
		1030692 ANK2_HUMAN (3-410): 7.95e-58: 208: 12.97		Q9H4D1_HUMAN (70-417): 2.85e-49: 180: 15.27
+	Hs
		1091461 ANK3_HUMAN (3-402): 1.92e-57: 207: 12.90		Q9H4D1_HUMAN (70-417): 2.85e-49: 180: 15.27
+	Mm
		109253 ANK3_MOUSE (2-360): 8.95e-53: 193: 14.57		ANK3_MOUSE (139-419): 2.68e-53: 193: 16.50
+	Hs
		920430 ANK2_HUMAN (3-410): 7.95e-58: 208: 12.97		DAPK1_HUMAN (6-220): 1.15e-43: 165: 14.42
+	Hs
		177203 ANK2_HUMAN (3-410): 7.95e-58: 208: 12.97		ANR28_HUMAN (10-258): 2.42e-43: 164: 14.24
+	Hs
		177209 ANK3_HUMAN (3-402): 1.92e-57: 207: 12.90		ANR28_HUMAN (10-258): 2.42e-43: 164: 14.24
+	Hs
		1432018 TNKS2_HUMAN (5-426): 6.04e-44: 167: 11.94		TNKS2_HUMAN (105-418): 8.93e-54: 194: 14.25
+	Mm
		1281839 MIB1_MOUSE (36-325): 2.04e-37: 148: 11.08		MIB1_MOUSE (20-328): 1.53e-53: 193: 14.73
+	Hs
		62979 POTEF_HUMAN (3-391): 7.44e-54: 196: 15.40		HACE1_HUMAN (73-403): 7.23e-37: 145: 14.11
+	Hs
		920472 DAPK1_HUMAN (4-198): 1.62e-37: 148: 19.18		MIB1_HUMAN (20-328): 2.68e-53: 193: 14.45
+	Hs
		177307 TNKS2_HUMAN (5-426): 6.04e-44: 167: 11.94		ANR28_HUMAN (10-258): 2.42e-43: 164: 14.24
+	Hs
		274188 ANKH1_HUMAN (24-415): 1.02e-44: 170: 14.94		ANR17_HUMAN (17-223): 1.26e-39: 153: 12.77
+	Hs
		920414 DAPK1_HUMAN (4-198): 1.62e-37: 148: 19.18		DAPK1_HUMAN (6-220): 1.15e-43: 165: 14.42
+	Mm
		1281840 MIB1_MOUSE (36-325): 2.04e-37: 148: 11.08		DAPK1_MOUSE (6-220): 3.64e-42: 160: 14.42