HitPredict

Interactor 1: Q4LE69 (Q4LE69)
Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67)
Gene: PIK4CA

Interactor 2: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	38270169
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 2121 Hs			1 391
+	Hs
		839505 PI4KA_HUMAN (49-2121): 0: 2740: 100.00		TXNIP_HUMAN (1-391): 1.41e-149: 430: 100.00
+	Hs
		1195678 Q4LE69_HUMAN (1-2121): 0: 2752: 100.00		ARRD3_HUMAN (2-383): 9.58e-131: 383: 40.35
+	Hs
		839492 PI4KA_HUMAN (49-2121): 0: 2740: 100.00		ARRD3_HUMAN (2-383): 9.58e-131: 383: 40.35
+	Hs
		1195665 Q4LE69_HUMAN (1-2121): 0: 2752: 100.00		ARRD4_HUMAN (5-383): 9.2e-123: 362: 43.99
+	Hs
		839482 PI4KA_HUMAN (49-2121): 0: 2740: 100.00		ARRD4_HUMAN (5-383): 9.2e-123: 362: 43.99
+	Hs
		839084 PK3CA_HUMAN (1461-2117): 1.73e-151: 500: 21.77		TXNIP_HUMAN (1-391): 1.41e-149: 430: 100.00
+	Dm
		1477140 TOR_DROME (1406-2075): 1.88e-121: 431: 13.47		Q9VI53_DROME (7-373): 6.21e-104: 315: 21.03
+	Dm
		1265726 Q7K3H0_DROME (1456-2117): 2.39e-130: 456: 19.42		Q8SYU5_DROME (8-380): 5.99e-89: 278: 16.75
+	Dm
		1476967 TOR_DROME (1406-2075): 1.88e-121: 431: 13.47		Q9VI00_DROME (8-379): 1.03e-93: 289: 21.91
+	Hs
		135891 P3C2A_HUMAN (1411-2120): 1.92e-150: 512: 17.85		ARRB2_HUMAN (15-323): 2.03e-60: 202: 12.18
+	Hs
		135901 P3C2A_HUMAN (1411-2120): 1.92e-150: 512: 17.85		ARRB1_HUMAN (25-358): 2.61e-56: 191: 12.95
+	Ce
		112161 PIKI1_CAEEL (1570-2119): 2.74e-118: 416: 17.34		O17981_CAEEL (10-356): 2.55e-90: 280: 19.13
+	Dm
		1265742 Q7K3H0_DROME (1456-2117): 2.39e-130: 456: 19.42		Q9VGU4_DROME (9-307): 1.82e-68: 226: 17.95