HitPredict

Interactor 1: THOC4 (Q86V81)
THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (Transcriptional coactivator Aly/REF) (bZIP-enhancing factor BEF)
Gene: ALYREF

Interactor 2: THOC1 (Q96FV9)
THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84)
Gene: THOC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.716

The method score is based on:

Property Details
Experiments 26496610, 30833792, 15998806, 17190602, 23299939
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000346 - transcription export complex
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 4 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 257
Hs

1 657
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024