HitPredict

Interactor 1: TAXB1 (Q86VP1)
Tax1-binding protein 1 (TRAF6-binding protein)
Gene: TAX1BP1

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0045087 - innate immune response GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 789 Hs			1 419
+	Hs
		1201869 TAXB1_HUMAN (1-789): 5.15e-85: 288: 100.00		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		1201957 TAXB1_HUMAN (1-789): 5.15e-85: 288: 100.00		MRCKB_HUMAN (39-356): 2.85e-10: 64.7: 13.60
+	Hs
		1025619 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		1025499 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		1137871 MRCKA_HUMAN (76-763): 9.09e-53: 201: 12.38		MRCKA_HUMAN (32-363): 1.19e-13: 75.1: 15.89
+	Hs
		1137917 MRCKA_HUMAN (76-763): 9.09e-53: 201: 12.38		MRCKB_HUMAN (39-356): 2.85e-10: 64.7: 13.60
+	Rn
		222476 MRCKA_RAT (76-763): 1.39e-52: 200: 12.52		MRCKB_RAT (45-355): 2.08e-10: 65: 14.56
+	Rn
		222472 MRCKA_RAT (76-763): 1.39e-52: 200: 12.52		MRCKA_RAT (77-391): 2.29e-09: 61.9: 16.30
+	Hs
		551687 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		724805 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		725151 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09
+	Hs
		528370 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYH6_HUMAN (4-395): 1.4e-09: 62.3: 11.48
+	Hs
		1025488 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89
+	Hs
		148359 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		148460 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		148461 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09
+	Hs
		148466 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MYH11_HUMAN (13-392): 2.7e-09: 61.5: 13.42
+	Hs
		149126 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89
+	Hs
		1268126 MRCKB_HUMAN (52-501): 2.47e-20: 99: 9.41		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89