HitPredict

Interactor 1: PDZ11 (Q5EBL8)
PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein)
Gene: PDZD11

Interactor 2: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 214
+	Hs
		988419 PDZ11_HUMAN (1-140): 2.8e-49: 156: 100.00		RAC1_HUMAN (22-214): 5.21e-81: 241: 58.03
+	Hs
		581090 PDZ11_HUMAN (1-140): 2.8e-49: 156: 100.00		RAC2_HUMAN (22-214): 1.82e-77: 232: 57.51
+	Hs
		953485 PDZ11_HUMAN (1-140): 2.8e-49: 156: 100.00		RAC3_HUMAN (22-195): 2.77e-76: 229: 62.64
+	Hs
		1104872 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RHOJ_HUMAN (1-214): 6.36e-83: 247: 100.00
+	Hs
		1118450 SNTB1_HUMAN (22-129): 5.31e-28: 109: 30.09		RHOJ_HUMAN (1-214): 6.36e-83: 247: 100.00
+	Hs
		988336 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RAC1_HUMAN (22-214): 5.21e-81: 241: 58.03
+	Hs
		601271 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RHOQ_HUMAN (17-213): 1.34e-80: 240: 78.00
+	Hs
		977979 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RHOB_HUMAN (23-214): 1.85e-80: 240: 48.44
+	Hs
		167687 LIN7A_HUMAN (39-137): 3.9e-30: 110: 38.61		RAC1_HUMAN (22-214): 5.21e-81: 241: 58.03
+	Hs
		601281 SNTB1_HUMAN (22-129): 5.31e-28: 109: 30.09		RHOQ_HUMAN (17-213): 1.34e-80: 240: 78.00
+	Hs
		977997 SNTB1_HUMAN (22-129): 5.31e-28: 109: 30.09		RHOB_HUMAN (23-214): 1.85e-80: 240: 48.44
+	Hs
		978189 RPGF6_HUMAN (46-125): 5.03e-28: 109: 37.04		RHOB_HUMAN (23-214): 1.85e-80: 240: 48.44
+	Hs
		962015 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RHOA_HUMAN (23-214): 3.34e-78: 234: 47.92
+	Hs
		1015413 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RHOG_HUMAN (20-214): 6.8e-78: 233: 50.26
+	Hs
		1439593 GOPC_HUMAN (23-137): 1.54e-27: 107: 29.06		V9HWD0_HUMAN (17-213): 1.34e-80: 240: 78.00
+	Hs
		601455 GOPC_HUMAN (23-137): 1.54e-27: 107: 29.06		RHOQ_HUMAN (17-213): 1.34e-80: 240: 78.00
+	Hs
		581023 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RAC2_HUMAN (22-214): 1.82e-77: 232: 57.51
+	Hs
		953424 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		RAC3_HUMAN (22-195): 2.77e-76: 229: 62.64
+	Hs
		955128 SNTB2_HUMAN (5-139): 8.5e-30: 114: 24.82		CDC42_HUMAN (20-214): 2.17e-76: 229: 61.03
+	Hs
		1015809 GOPC_HUMAN (23-137): 1.54e-27: 107: 29.06		RHOG_HUMAN (20-214): 6.8e-78: 233: 50.26