HitPredict

Interactor 1: LRAD1 (Q5T700)
Low-density lipoprotein receptor class A domain-containing protein 1
Gene: LDLRAD1

Interactor 2: LRP10 (Q7Z4F1)
Low-density lipoprotein receptor-related protein 10 (LRP-10)
Gene: LRP10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CUB~Ldl_recept_a, Ldl_recept_a~Ldl_recept_a
Common GO terms	GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 713
+	Hs
		1366653 SORL_HUMAN (13-203): 2.08e-44: 159: 21.72		SORL_HUMAN (110-495): 3.65e-52: 198: 13.93
+	Hs
		1022528 VLDLR_HUMAN (2-171): 1.73e-29: 116: 16.67		ST14_HUMAN (6-323): 8.38e-38: 153: 14.54
+	Hs
		1022510 VLDLR_HUMAN (2-171): 1.73e-29: 116: 16.67		VLDLR_HUMAN (224-509): 2.31e-35: 145: 18.28
+	Hs
		1022515 VLDLR_HUMAN (2-171): 1.73e-29: 116: 16.67		LRP8_HUMAN (106-365): 5.61e-29: 125: 12.30
+	Hs
		376568 LDLR_HUMAN (118-204): 1.1e-15: 76.6: 26.44		ST14_HUMAN (6-323): 8.38e-38: 153: 14.54
+	Hs
		1120561 LRP8_HUMAN (5-171): 8.19e-24: 100: 16.30		LRP8_HUMAN (106-365): 5.61e-29: 125: 12.30
+	Hs
		376501 LRP8_HUMAN (5-171): 8.19e-24: 100: 16.30		LDLR_HUMAN (52-329): 1.33e-22: 105: 11.00
+	Hs
		376455 LDLR_HUMAN (118-204): 1.1e-15: 76.6: 26.44		LDLR_HUMAN (52-329): 1.33e-22: 105: 11.00
+	Hs
		274844 LRP6_HUMAN (1-120): 6.6e-27: 109: 14.18		LRP5_HUMAN (84-185): 7.08e-09: 61.5: 22.33
+	Hs
		287502 LRP6_HUMAN (1-120): 6.6e-27: 109: 14.18		LRP6_HUMAN (72-186): 6.28e-09: 61.5: 16.26
+	Hs
		376497 LDLR_HUMAN (118-204): 1.1e-15: 76.6: 26.44		LRP1_HUMAN (208-461): 4.94e-09: 62.3: 10.37
+	Hs
		1491782 ST14_HUMAN (10-82): 1.11e-10: 62: 13.48		TLL2_HUMAN (25-143): 7.55e-13: 74.2: 15.39