HitPredict

Interactor 1: DRC8 (Q5VUJ9)
Dynein regulatory complex protein 8 (EF-hand calcium-binding domain-containing protein 2)
Gene: EFCAB2

Interactor 2: UBE3B (Q7Z3V4)
Ubiquitin-protein ligase E3B (EC 2.3.2.26) (HECT-type ubiquitin transferase E3B)
Gene: UBE3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 1068
+	Hs
		692731 CALL3_HUMAN (144-268): 6.63e-46: 152: 32.00		UBE3B_HUMAN (1-1068): 0: 1413: 100.00
+	Hs
		516352 CALM1_HUMAN (143-268): 3.79e-41: 140: 33.33		UBE3B_HUMAN (1-1068): 0: 1413: 100.00
+	Hs
		516426 CALM2_HUMAN (143-268): 3.79e-41: 140: 33.33		UBE3B_HUMAN (1-1068): 0: 1413: 100.00
+	Dm
		968597 CALM_DROME (143-268): 1.01e-40: 139: 34.13		Q9VSS9_DROME (4-1068): 0: 1163: 47.92
+	Dm
		121083 CALM_DROME (143-268): 1.01e-40: 139: 34.13		M9PEV2_DROME (4-1068): 0: 1161: 47.78
+	At
		1043050 CALM6_ARATH (144-268): 2.32e-46: 153: 33.60		UPL6_ARATH (12-1068): 0: 969: 27.62
+	At
		515499 CALM4_ARATH (143-268): 1.35e-38: 133: 34.13		UPL6_ARATH (12-1068): 0: 969: 27.62
+	Hs
		516341 CALM1_HUMAN (143-268): 3.79e-41: 140: 33.33		UBE3C_HUMAN (6-1068): 0: 579: 25.55
+	Hs
		516415 CALM2_HUMAN (143-268): 3.79e-41: 140: 33.33		UBE3C_HUMAN (6-1068): 0: 579: 25.55
+	Hs
		516521 CALM3_HUMAN (143-268): 3.79e-41: 140: 33.33		UBE3C_HUMAN (6-1068): 0: 579: 25.55
+	Sc
		449129 CALM_YEAST (71-218): 1.29e-39: 136: 19.60		RSP5_YEAST (604-1066): 8.15e-154: 479: 27.31
+	Hs
		692828 CALL3_HUMAN (144-268): 6.63e-46: 152: 32.00		HECW2_HUMAN (645-1067): 1.47e-140: 462: 31.22
+	Sc
		449152 CALM_YEAST (71-218): 1.29e-39: 136: 19.60		HUL5_YEAST (509-1068): 4.52e-64: 236: 31.46