HitPredict

Interactor 1: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: PSPC1 (Q8R326)
Paraspeckle component 1 (Paraspeckle protein 1) (mPSP1)
Gene: PSPC1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 217 Mm			1 523
+	Hs
		987655 GRB2_HUMAN (1-217): 4.48e-72: 219: 99.54		NONO_HUMAN (49-523): 4.37e-64: 217: 57.47
+	Hs
		655191 PTK6_HUMAN (4-141): 7.17e-23: 97.1: 38.93		SFPQ_HUMAN (52-523): 6.69e-79: 262: 56.63
+	Hs
		550216 GRB2_HUMAN (1-217): 4.48e-72: 219: 99.54		PABP1_HUMAN (145-428): 1.53e-23: 106: 10.96
+	Hs
		1360524 VAV3_HUMAN (3-57): 6.01e-13: 69: 38.18		PSPC1_HUMAN (1-523): 2.02e-76: 251: 96.95
+	Mm
		1221243 GRB2_MOUSE (1-217): 1.59e-72: 220: 100.00		RBM4_MOUSE (82-189): 3.36e-09: 60.5: 33.04
+	Hs
		987915 GRB2_HUMAN (1-217): 4.48e-72: 219: 99.54		RBM4_HUMAN (82-189): 5e-09: 60.1: 32.14
+	Hs
		557280 SRC_HUMAN (160-215): 2.32e-11: 64.2: 31.03		PABP4_HUMAN (4-439): 1.17e-48: 179: 12.21
+	Ce
		711453 SEM5_CAEEL (3-65): 2.3e-14: 71.1: 31.75		Q17350_CAEEL (2-424): 6.65e-43: 163: 14.29
+	Hs
		550100 SRC_HUMAN (160-215): 2.32e-11: 64.2: 31.03		PABP1_HUMAN (145-428): 1.53e-23: 106: 10.96
+	Hs
		557468 SRC_HUMAN (160-215): 2.32e-11: 64.2: 31.03		PABP3_HUMAN (145-428): 2.7e-22: 102: 9.59
+	Mm
		813531 FYN_MOUSE (161-215): 1.26e-13: 70.8: 31.58		RAVR1_MOUSE (36-233): 5.05e-15: 79.9: 23.36
+	Hs
		292848 GRAP2_HUMAN (3-55): 7.11e-11: 62.5: 39.62		RAVR1_HUMAN (83-233): 3.47e-14: 77.2: 23.35
+	Hs
		463106 YES_HUMAN (161-215): 4.3e-12: 66.5: 28.07		ELAV1_HUMAN (83-155): 3.23e-13: 72.6: 29.11