HitPredict

Interactor 1: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1101 Hs			1 601
+	Hs
		297521 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		TOX4_HUMAN (339-528): 4.7e-37: 148: 24.76
+	Hs
		996761 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		449766 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		643368 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		1221662 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		175784 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		HMGB3_HUMAN (411-495): 5.79e-12: 67.2: 21.84
+	Hs
		1199219 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		818618 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Mm
		818763 SMC3_MOUSE (51-1061): 1.42e-81: 292: 13.91		SOX2_MOUSE (375-551): 5.31e-32: 128: 16.38
+	Hs
		1301004 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		311503 SMC2_HUMAN (51-1055): 9.8e-55: 210: 11.41		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Hs
		725110 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57