HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0046872 - metal ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1834 Hs			1 777
+	Hs
		1219779 SLX4_HUMAN (1-1834): 0: 1486: 100.00		ANKH1_HUMAN (114-664): 2.01e-66: 242: 14.16
+	Hs
		257654 SLX4_HUMAN (1-1834): 0: 1486: 100.00		ANR17_HUMAN (177-599): 3.04e-64: 236: 15.72
+	Hs
		1167268 SLX4_HUMAN (1-1834): 0: 1486: 100.00		BCOR_HUMAN (152-543): 1.16e-44: 176: 23.93
+	Hs
		801335 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		1056954 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Mm
		103608 ANK2_MOUSE (780-1802): 1.6e-50: 200: 12.23		ANK3_MOUSE (104-622): 8.12e-77: 273: 14.69
+	Hs
		862028 ANK2_HUMAN (1147-1751): 8.46e-11: 69.7: 10.18		DAPK1_HUMAN (194-574): 1.25e-79: 281: 15.62
+	Mm
		103609 MICA3_MOUSE (1157-1828): 3.03e-11: 71.3: 11.98		ANK3_MOUSE (104-622): 8.12e-77: 273: 14.69
+	Hs
		1056981 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		TNKS2_HUMAN (396-760): 1.04e-52: 200: 18.97
+	Hs
		166913 ANK2_HUMAN (1147-1751): 8.46e-11: 69.7: 10.18		ANR28_HUMAN (221-515): 1.02e-47: 185: 17.16
+	Hs
		310053 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		TNKS1_HUMAN (364-552): 9.86e-28: 122: 23.98
+	Hs
		1191810 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		ANS1B_HUMAN (217-465): 5.44e-27: 120: 12.11
+	Hs
		1170104 SRCAP_HUMAN (1206-1787): 5.26e-09: 64: 11.45		X5D778_HUMAN (410-509): 9.46e-22: 100: 51.00
+	Hs
		965154 ANK2_HUMAN (1147-1751): 8.46e-11: 69.7: 10.18		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		883487 ANK2_HUMAN (1147-1751): 8.46e-11: 69.7: 10.18		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59
+	Hs
		1336188 MAGE1_HUMAN (1023-1409): 1.03e-12: 75.8: 14.18		KDIS_HUMAN (202-402): 5.56e-14: 78.4: 11.43
+	Hs
		276200 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		PSD10_HUMAN (272-468): 6e-18: 85.3: 11.94