HitPredict

Interactor 1: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Interactor 2: BRK1 (Q8WUW1)
Protein BRICK1 (BRK1)
Gene: BRK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0030027 - lamellipodium GO:0031209 - SCAR complex GO:0070062 - extracellular exosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 75
+	Mm
		1208101 ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93		BRK1_MOUSE (1-75): 4.28e-36: 117: 98.67
+	Hs
		1260607 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		BRK1_HUMAN (1-75): 1.59e-36: 119: 100.00
+	Dm
		1228540 Q9Y0S9_DROME (1-504): 2.01e-77: 252: 34.72		Q8MLQ0_DROME (2-75): 7.14e-36: 117: 72.97