HitPredict

Interactor 1: RPB2 (P08518)
DNA-directed RNA polymerase II subunit RPB2 (RNA polymerase II subunit 2) (EC 2.7.7.6) (B150) (DNA-directed RNA polymerase II 140 kDa polypeptide)
Gene: RPB2

Interactor 2: RPB7 (P34087)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (B16)
Gene: RPB7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 11805826, 16429126, 10082533, 19394294, 37968396, 20720002, 23418395, 24358479, 24513203
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb2_7~S1, RNA_pol_Rpb2_7~SHS2_Rpb7-N
Common GO terms GO:0001172 - RNA-templated transcription
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1224
Sc

1 171
+ Hs
+ Hs
+ Sp
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+ Hs
+ Hs
+ Dm
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+ Pf
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+ Hs

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Last updated: 15 Jul 2024