HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	30196744, 29634390
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Hs			1 488
+	Hs
		1109815 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		188303 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		1368046 SNR40_HUMAN (175-514): 4.64e-64: 216: 16.81		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		965127 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		964922 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1227626 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04
+	Mm
		1000026 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		HDAC2_MOUSE (1-488): 0: 704: 99.39
+	Hs
		261430 TBL1X_HUMAN (468-607): 8.64e-25: 110: 19.87		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		188229 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		148721 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Dm
		1269416 EBI_DROME (254-478): 1.49e-54: 199: 19.17		Q7KTS4_DROME (10-430): 0: 560: 57.11
+	Dm
		1377789 EBI_DROME (254-478): 1.49e-54: 199: 19.17		Q9VNC2_DROME (10-430): 0: 556: 56.88
+	Hs
		261406 TBL1X_HUMAN (468-607): 8.64e-25: 110: 19.87		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1110051 TBL1R_HUMAN (479-607): 3.68e-24: 108: 18.71		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		188125 TBL1X_HUMAN (468-607): 8.64e-25: 110: 19.87		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		188361 TBL1R_HUMAN (479-607): 3.68e-24: 108: 18.71		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		984317 GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30		HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04
+	Hs
		983606 GBB1_HUMAN (165-516): 2.35e-43: 160: 17.18		HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04
+	Hs
		1437753 GBB4_HUMAN (165-516): 2.18e-42: 157: 16.07		HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04
+	Hs
		261429 TBL1X_HUMAN (468-607): 8.64e-25: 110: 19.87		HDAC7_HUMAN (29-280): 1.97e-23: 106: 26.37