HitPredict

Interactor 1: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	23953116
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1335 Hs			1 1193
+	Hs
		724912 RPTOR_HUMAN (1-1335): 0: 1440: 100.00		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		1067456 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		EEA1_HUMAN (691-1193): 8.44e-18: 91.8: 12.35
+	Hs
		1268063 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		1189782 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		MYH14_HUMAN (449-1088): 6.07e-13: 75.8: 14.74
+	Hs
		1068625 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		551655 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		725215 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		724952 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		903399 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		903334 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		MYH14_HUMAN (449-1088): 6.07e-13: 75.8: 14.74
+	Hs
		903240 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		551632 LIS1_HUMAN (1101-1334): 4.69e-55: 199: 15.69		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		148610 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		528407 TLE3_HUMAN (1165-1335): 2.38e-23: 109: 13.07		MYH8_HUMAN (287-953): 3.4e-31: 135: 11.77
+	Hs
		522544 TLE3_HUMAN (1165-1335): 2.38e-23: 109: 13.07		MYH1_HUMAN (287-962): 1.25e-30: 133: 11.18
+	Hs
		980924 TLE3_HUMAN (1165-1335): 2.38e-23: 109: 13.07		MYH4_HUMAN (291-1062): 2.67e-30: 132: 12.19
+	Hs
		502910 TLE3_HUMAN (1165-1335): 2.38e-23: 109: 13.07		MYH3_HUMAN (173-1134): 9.39e-30: 131: 11.22
+	Hs
		980905 TLE3_HUMAN (1165-1335): 2.38e-23: 109: 13.07		MYH2_HUMAN (192-1011): 9.96e-28: 124: 10.37
+	Hs
		551766 WDR5B_HUMAN (1200-1334): 8.32e-30: 123: 11.77		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		522607 TLE3_HUMAN (1165-1335): 2.38e-23: 109: 13.07		MYH7_HUMAN (154-896): 6.03e-22: 105: 11.91