Interactor 1: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Interactor 2: LST8 (Q9BVC4)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Gene: MLST8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 12408816, 28489822, 27909983, 20562859, 18030348, 25940091, 24036451, 19299511, 20169205, 16798736, 17565979, 21321085, 24403073, 26678875, 16919458, 12718876
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0006974 - DNA damage response
and 12 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1335
Hs

1 326
+ Mm
+ At
+ At
+ At
+ At
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024