HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: SWP70 (Q9UH65)
Switch-associated protein 70 (SWAP-70)
Gene: SWAP70

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	30196744, 31015422
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 585
+	Hs
		1227455 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		DEFI6_HUMAN (3-542): 4.77e-118: 365: 46.00
+	Hs
		1227112 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		CIP2A_HUMAN (283-561): 1.03e-40: 160: 17.99
+	Hs
		1226865 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		MRCKG_HUMAN (358-584): 7.7e-14: 77.2: 10.73
+	Hs
		1227621 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		EP15R_HUMAN (431-585): 1.07e-13: 76.4: 12.26
+	Hs
		1227440 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		TARA_HUMAN (261-583): 9.5e-11: 67.2: 13.89
+	Hs
		1143156 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		PLEC_HUMAN (316-521): 1.2e-10: 67.1: 22.28
+	Mm
		1230035 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		SWP70_MOUSE (1-585): 3.7e-123: 377: 95.04
+	Mm
		1297685 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		DEFI6_MOUSE (3-542): 1.61e-111: 348: 46.18
+	Dm
		1377785 EBI_DROME (254-478): 1.49e-54: 199: 19.17		Q9VIF7_DROME (175-544): 5.72e-35: 143: 12.04
+	Hs
		64407 SNR40_HUMAN (175-514): 4.64e-64: 216: 16.81		A6H8W8_HUMAN (142-585): 3.13e-23: 107: 11.66
+	Hs
		157718 SNR40_HUMAN (175-514): 4.64e-64: 216: 16.81		CTRO_HUMAN (234-585): 7.7e-10: 64.1: 10.35
+	Hs
		964961 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		PLEC_HUMAN (316-521): 1.2e-10: 67.1: 22.28
+	Hs
		965122 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		MY18A_HUMAN (271-584): 1.57e-10: 66.4: 14.61
+	Hs
		157170 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		CTRO_HUMAN (234-585): 7.7e-10: 64.1: 10.35
+	Hs
		772720 GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30		MYH9_HUMAN (237-570): 5.48e-09: 61.4: 13.65
+	Hs
		1349423 POC1B_HUMAN (182-359): 1.25e-15: 81.7: 15.08		CIP2A_HUMAN (283-561): 1.03e-40: 160: 17.99
+	Hs
		157870 GBB4_HUMAN (165-516): 2.18e-42: 157: 16.07		CTRO_HUMAN (234-585): 7.7e-10: 64.1: 10.35
+	Mm
		1221958 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		EP15R_MOUSE (431-585): 7.12e-13: 73.7: 12.26
+	Mm
		1297934 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		PLEC_MOUSE (295-575): 4.16e-09: 62.1: 16.84