HitPredict

Interactor 1: RYBP (Q8N488)
RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1)
Gene: RYBP

Interactor 2: AUTS2 (Q8WXX7)
Autism susceptibility gene 2 protein
Gene: AUTS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	25519132, 26186194, 28514442, 27705803, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 228 Hs			1 1259
+	Hs
		1222200 YAF2_HUMAN (3-227): 3.24e-55: 176: 52.89		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Mm
		1161098 RYBP_MOUSE (1-228): 1.71e-61: 193: 99.12		Q6PED7_MOUSE (637-1259): 1.68e-63: 230: 92.01
+	Hs
		1233212 RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		1222227 YAF2_HUMAN (3-227): 3.24e-55: 176: 52.89		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		1233209 RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1222223 YAF2_HUMAN (3-227): 3.24e-55: 176: 52.89		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		62112 RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00		F186A_HUMAN (171-824): 3.47e-10: 66.9: 16.07