HitPredict

Interactor 1: CPSF7 (Q8N684)
Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit)
Gene: CPSF7

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 471 Hs			1 523
+	Hs
		1069746 CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613519 CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1084547 CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Mm
		1156796 CPSF6_MOUSE (1-451): 8.75e-77: 251: 39.51		NONO_MOUSE (45-523): 1.13e-66: 224: 57.83
+	Hs
		1077418 CPSF7_HUMAN (1-456): 1.39e-122: 367: 100.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1031404 PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1077379 CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Mm
		1156792 CPSF6_MOUSE (1-451): 8.75e-77: 251: 39.51		RBM4_MOUSE (83-190): 3.35e-09: 60.5: 33.04
+	Hs
		1084591 CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51		RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04
+	Hs
		516689 PABP3_HUMAN (83-184): 4.77e-13: 73.4: 19.61		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1084602 CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		516495 PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		516339 PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Sc
		376562 PABP_YEAST (83-159): 2.45e-16: 83.4: 24.68		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		1119141 PAP1L_HUMAN (73-164): 1.12e-12: 72.3: 19.57		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		474021 PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28		PAB4L_HUMAN (147-425): 7.96e-26: 110: 13.89
+	Hs
		1077516 RBM12_HUMAN (70-286): 4.33e-19: 92.6: 18.43		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1020249 PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1031344 PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		516484 PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65